Table 2 The 40 most significant associations between the GO terms and genes of the ZGA cluster
GO identifier | GO term definition | Nb genes in | Genes at | GO class coverage | e-value |
|---|---|---|---|---|---|
| Â | Â | GO class | intersection | by cluster | Â |
GO:0009653 | BP: anatomical structure morphogenesis | 1521 | 145 | 10% | 8.00E-31 |
GO:0007275 | BP: multicellular organismal development | 2739 | 195 | 7% | 9.50E-30 |
GO:0048513 | BP: organ development | 1239 | 128 | 10% | 4.10E-29 |
GO:0065007 | BP: biological regulation | 2287 | 176 | 8% | 1.20E-28 |
GO:0048856 | BP: anatomical structure development | 2734 | 192 | 7% | 8.40E-28 |
GO:0032502 | BP: developmental process | 3056 | 202 | 7% | 7.60E-27 |
GO:0009790 | BP: embryo development | 595 | 84 | 14% | 1.20E-25 |
GO:0048731 | BP: system development | 2161 | 166 | 8% | 1.60E-25 |
GO:0050789 | BP: regulation of biological process | 2075 | 162 | 8% | 2.70E-25 |
GO:0045165 | BP: cell fate commitment | 222 | 50 | 23% | 8.80E-23 |
GO:0007389 | BP: pattern specification process | 512 | 73 | 14% | 8.90E-22 |
GO:0048699 | BP: generation of neurons | 599 | 79 | 13% | 1.00E-21 |
GO:0050794 | BP: regulation of cellular process | 1910 | 148 | 8% | 3.50E-21 |
GO:0001071 | MF: nucleic acid binding transcription factor activity | 301 | 53 | 18% | 4.80E-21 |
GO:0003700 | MF: sequence-specific DNA binding transcription factor activity | 301 | 53 | 18% | 4.80E-21 |
GO:0003002 | BP: regionalization | 479 | 69 | 14% | 1.40E-20 |
GO:0048598 | BP: embryonic morphogenesis | 232 | 48 | 21% | 5.50E-20 |
GO:0001709 | BP: cell fate determination | 123 | 36 | 29% | 1.10E-19 |
GO:0006355 | BP: regulation of transcription, DNA-dependent | 517 | 68 | 13% | 7.00E-18 |
GO:0048869 | BP: cellular developmental process | 1732 | 133 | 8% | 2.70E-17 |
GO:0030154 | BP: cell differentiation | 1695 | 131 | 8% | 4.00E-17 |
GO:0051252 | BP: regulation of RNA metabolic process | 586 | 71 | 12% | 9.10E-17 |
GO:0009887 | BP: organ morphogenesis | 665 | 76 | 11% | 9.90E-17 |
GO:0007369 | BP: gastrulation | 69 | 26 | 38% | 1.30E-16 |
GO:0009888 | BP: tissue development | 532 | 67 | 13% | 1.70E-16 |
GO:2000112 | BP: regulation of cellular macromolecule biosynthetic process | 588 | 70 | 12% | 5.00E-16 |
GO:0010556 | BP: regulation of macromolecule biosynthetic process | 588 | 70 | 12% | 5.00E-16 |
GO:0019219 | BP: regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 609 | 71 | 12% | 8.50E-16 |
GO:0051171 | BP: regulation of nitrogen compound metabolic process | 611 | 71 | 12% | 1.00E-15 |
GO:0032501 | BP: multicellular organismal process | 3730 | 206 | 6% | 1.50E-15 |
GO:0010468 | BP: regulation of gene expression | 725 | 77 | 11% | 4.60E-15 |
GO:0048729 | BP: tissue morphogenesis | 305 | 48 | 16% | 1.10E-14 |
GO:0031326 | BP: regulation of cellular biosynthetic process | 633 | 70 | 11% | 3.20E-14 |
GO:0048569 | BP: post-embryonic organ development | 340 | 50 | 15% | 3.70E-14 |
GO:0009889 | BP: regulation of biosynthetic process | 635 | 70 | 11% | 3.80E-14 |
GO:0030182 | BP: neuron differentiation | 514 | 62 | 12% | 5.60E-14 |
GO:0060255 | BP: regulation of macromolecule metabolic process | 838 | 81 | 10% | 1.40E-13 |
GO:0060429 | BP: epithelium development | 291 | 45 | 15% | 2.90E-13 |
GO:0009880 | BP: embryonic pattern specification | 231 | 40 | 17% | 3.40E-13 |
GO:0031323 | BP: regulation of cellular metabolic process | 819 | 79 | 10% | 4.70E-13 |