Skip to main content

Advertisement

Table 2 The 40 most significant associations between the GO terms and genes of the ZGA cluster

From: Transcriptional and epigenetic signatures of zygotic genome activation during early drosophila embryogenesis

GO identifier GO term definition Nb genes in Genes at GO class coverage e-value
   GO class intersection by cluster  
GO:0009653 BP: anatomical structure morphogenesis 1521 145 10% 8.00E-31
GO:0007275 BP: multicellular organismal development 2739 195 7% 9.50E-30
GO:0048513 BP: organ development 1239 128 10% 4.10E-29
GO:0065007 BP: biological regulation 2287 176 8% 1.20E-28
GO:0048856 BP: anatomical structure development 2734 192 7% 8.40E-28
GO:0032502 BP: developmental process 3056 202 7% 7.60E-27
GO:0009790 BP: embryo development 595 84 14% 1.20E-25
GO:0048731 BP: system development 2161 166 8% 1.60E-25
GO:0050789 BP: regulation of biological process 2075 162 8% 2.70E-25
GO:0045165 BP: cell fate commitment 222 50 23% 8.80E-23
GO:0007389 BP: pattern specification process 512 73 14% 8.90E-22
GO:0048699 BP: generation of neurons 599 79 13% 1.00E-21
GO:0050794 BP: regulation of cellular process 1910 148 8% 3.50E-21
GO:0001071 MF: nucleic acid binding transcription factor activity 301 53 18% 4.80E-21
GO:0003700 MF: sequence-specific DNA binding transcription factor activity 301 53 18% 4.80E-21
GO:0003002 BP: regionalization 479 69 14% 1.40E-20
GO:0048598 BP: embryonic morphogenesis 232 48 21% 5.50E-20
GO:0001709 BP: cell fate determination 123 36 29% 1.10E-19
GO:0006355 BP: regulation of transcription, DNA-dependent 517 68 13% 7.00E-18
GO:0048869 BP: cellular developmental process 1732 133 8% 2.70E-17
GO:0030154 BP: cell differentiation 1695 131 8% 4.00E-17
GO:0051252 BP: regulation of RNA metabolic process 586 71 12% 9.10E-17
GO:0009887 BP: organ morphogenesis 665 76 11% 9.90E-17
GO:0007369 BP: gastrulation 69 26 38% 1.30E-16
GO:0009888 BP: tissue development 532 67 13% 1.70E-16
GO:2000112 BP: regulation of cellular macromolecule biosynthetic process 588 70 12% 5.00E-16
GO:0010556 BP: regulation of macromolecule biosynthetic process 588 70 12% 5.00E-16
GO:0019219 BP: regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 609 71 12% 8.50E-16
GO:0051171 BP: regulation of nitrogen compound metabolic process 611 71 12% 1.00E-15
GO:0032501 BP: multicellular organismal process 3730 206 6% 1.50E-15
GO:0010468 BP: regulation of gene expression 725 77 11% 4.60E-15
GO:0048729 BP: tissue morphogenesis 305 48 16% 1.10E-14
GO:0031326 BP: regulation of cellular biosynthetic process 633 70 11% 3.20E-14
GO:0048569 BP: post-embryonic organ development 340 50 15% 3.70E-14
GO:0009889 BP: regulation of biosynthetic process 635 70 11% 3.80E-14
GO:0030182 BP: neuron differentiation 514 62 12% 5.60E-14
GO:0060255 BP: regulation of macromolecule metabolic process 838 81 10% 1.40E-13
GO:0060429 BP: epithelium development 291 45 15% 2.90E-13
GO:0009880 BP: embryonic pattern specification 231 40 17% 3.40E-13
GO:0031323 BP: regulation of cellular metabolic process 819 79 10% 4.70E-13
  1. Hypergeometric E-value (expected number of false positives) was computed with the RSAT tool, compare-classes[19].