Figure 8From: Integrated “omics” profiling indicates that miRNAs are modulators of the ontogenetic venom composition shift in the Central American rattlesnake, Crotalus simus simusPredicted miRNA binding features. miRanda alignment of miRNAs from adult (Ad) and newborn (New) venom gland transcriptomes and their predicted target mRNA loci listed in Figure 7, showing their Watson-Crick pairing to 3'-UTR loci of PLA2 and SVMP 454 transcripts, and the MapMi-calculated binding energies. The adult-specific miRNA targeting crotoxin B-subunit is highlight in red; the miRNA selectively found in the newborn dataset and targeting a SVMP mRNA is colored blue. Nucleotide positions within the best BLAST hit in the NCBI database are indicated.Back to article page