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Table 1 Number of mapped reads and read depth obtained through exome sequencing of 11 mouse strains

From: Exome sequencing of senescence-accelerated mice (SAM) reveals deleterious mutations in degenerative disease-causing genes

Strains

SAMP1/ TaSlc

SAMP3/ SlcIdr

SAMP6/ TaSlc

SAMP8/ TaSlc

SAMP10/ TaSlc

SAMP11/ SlcIdr

SAMR1/ SlcIdr

SAMR1/ TaSlc

SAMR3B/ SlcIdr

AKR/J

C57BL/6J

Average

Targeted exons

221,784

221,784

221,784

221,784

221,784

221,784

221,784

221,784

221,784

221,784

221,784

221,784

Target exons with no coverage

7,740

7,132

6,945

7,004

7,238

6,867

6,924

6,332

7,165

7,557

7,384

7,117

Total Target bases

51,555,503

51,555,503

51,555,503

51,555,503

51,555,503

51,555,503

51,555,503

51,555,503

51,555,503

51,555,503

51,555,503

51,555,503

Target bases not covered

4,530,669

4,368,898

4,182,707

4,142,933

4,167,472

3,987,407

4,013,747

3,824,098

4,138,242

4,334,915

4,556,739

4,204,348

Percent of target bases not covered

8.8%

8.5%

8.1%

8.0%

8.1%

7.7%

7.8%

7.4%

8.0%

8.4%

8.8%

8.2%

Total reads

51,745,673

35,778,184

46,935,236

49,808,616

46,543,914

60,395,876

55,759,506

92,605,357

59,459,968

33,681,727

33,076,734

51,435,526

Reads in target regions

37,488,887

30,022,764

38,828,147

39,487,865

35,776,159

44,391,567

43,666,102

76,028,527

42,978,757

23,655,073

24,442,946

39,706,072

Reads off target regions

14,256,786

5,755,420

8,107,089

10,320,751

10,767,755

16,004,309

12,093,404

16,576,830

16,481,211

10,026,654

8,633,788

11,729,454

Percent of reads in target regions

72.4%

83.9%

82.7%

79.3%

76.9%

73.5%

78.3%

82.1%

72.3%

70.2%

73.9%

76.9%

Coverage at 1×

91.2%

91.5%

91.9%

92.0%

91.9%

92.3%

92.2%

92.6%

92.0%

91.6%

91.2%

91.8%

Coverage at 5×

83.0%

81.6%

84.4%

85.2%

84.8%

86.6%

86.5%

89.0%

86.3%

80.5%

79.9%

84.4%

Coverage at 10×

71.4%

67.1%

73.2%

74.6%

73.4%

77.6%

77.4%

84.0%

77.4%

63.1%

62.9%

72.9%

Coverage at 20×

49.6%

41.6%

50.9%

52.9%

50.0%

57.6%

57.2%

72.3%

57.6%

34.6%

35.1%

50.9%

Average depth of coverage within target regions

31.0×

25.3×

32.7×

33.0×

29.6×

37.0×

36.3×

63.7×

35.3×

19.5×

20.2×

33.1×