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Table 1 Number of mapped reads and read depth obtained through exome sequencing of 11 mouse strains

From: Exome sequencing of senescence-accelerated mice (SAM) reveals deleterious mutations in degenerative disease-causing genes

Strains SAMP1/ TaSlc SAMP3/ SlcIdr SAMP6/ TaSlc SAMP8/ TaSlc SAMP10/ TaSlc SAMP11/ SlcIdr SAMR1/ SlcIdr SAMR1/ TaSlc SAMR3B/ SlcIdr AKR/J C57BL/6J Average
Targeted exons 221,784 221,784 221,784 221,784 221,784 221,784 221,784 221,784 221,784 221,784 221,784 221,784
Target exons with no coverage 7,740 7,132 6,945 7,004 7,238 6,867 6,924 6,332 7,165 7,557 7,384 7,117
Total Target bases 51,555,503 51,555,503 51,555,503 51,555,503 51,555,503 51,555,503 51,555,503 51,555,503 51,555,503 51,555,503 51,555,503 51,555,503
Target bases not covered 4,530,669 4,368,898 4,182,707 4,142,933 4,167,472 3,987,407 4,013,747 3,824,098 4,138,242 4,334,915 4,556,739 4,204,348
Percent of target bases not covered 8.8% 8.5% 8.1% 8.0% 8.1% 7.7% 7.8% 7.4% 8.0% 8.4% 8.8% 8.2%
Total reads 51,745,673 35,778,184 46,935,236 49,808,616 46,543,914 60,395,876 55,759,506 92,605,357 59,459,968 33,681,727 33,076,734 51,435,526
Reads in target regions 37,488,887 30,022,764 38,828,147 39,487,865 35,776,159 44,391,567 43,666,102 76,028,527 42,978,757 23,655,073 24,442,946 39,706,072
Reads off target regions 14,256,786 5,755,420 8,107,089 10,320,751 10,767,755 16,004,309 12,093,404 16,576,830 16,481,211 10,026,654 8,633,788 11,729,454
Percent of reads in target regions 72.4% 83.9% 82.7% 79.3% 76.9% 73.5% 78.3% 82.1% 72.3% 70.2% 73.9% 76.9%
Coverage at 1× 91.2% 91.5% 91.9% 92.0% 91.9% 92.3% 92.2% 92.6% 92.0% 91.6% 91.2% 91.8%
Coverage at 5× 83.0% 81.6% 84.4% 85.2% 84.8% 86.6% 86.5% 89.0% 86.3% 80.5% 79.9% 84.4%
Coverage at 10× 71.4% 67.1% 73.2% 74.6% 73.4% 77.6% 77.4% 84.0% 77.4% 63.1% 62.9% 72.9%
Coverage at 20× 49.6% 41.6% 50.9% 52.9% 50.0% 57.6% 57.2% 72.3% 57.6% 34.6% 35.1% 50.9%
Average depth of coverage within target regions 31.0× 25.3× 32.7× 33.0× 29.6× 37.0× 36.3× 63.7× 35.3× 19.5× 20.2× 33.1×