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Table 2 Number of SNVs identified through exome sequencing of 11 mouse strains

From: Exome sequencing of senescence-accelerated mice (SAM) reveals deleterious mutations in degenerative disease-causing genes

Strains SAMP1/ TaSlc SAMP3/ SlcIdr SAMP6/ TaSlc SAMP8/ TaSlc SAMP10/ TaSlc SAMP11/ SlcIdr SAMR1/ SlcIdr SAMR1/ TaSlc SAMR3B/ SlcIdr AKR/J C57BL/6J
Total SNVs 112245 85198 90734 97039 106341 104290 108059 108880 121527 100463 3484
 Exonic SNVs 35791 32019 32659 34048 35752 35817 36174 38432 38925 32816 1407
 Homozygous 28916 26142 27914 26142 29282 29310 30253 25891 31338 26880 158
 Non-synonymous 7364 6811 7106 7435 7429 7413 7588 6507 7843 6903 63
 Novel 310 260 316 273 317 286 317 230 491 245 39
Total MNVs 2251 1610 1757 1870 2093 2007 2207 2210 2245 1834 67
 Exonic MNVs 529 433 478 473 528 511 535 571 539 407 22
 Homozygous 404 346 375 393 428 412 406 420 417 349 14
 Non-synonymous 258 228 243 260 279 273 262 274 294 215 12
 Novel 49 33 48 43 50 48 51 63 32 32 8
Total Indels 4439 3189 3653 3932 4446 4286 4749 4287 4943 3988 111
 Exonic Indels 470 371 406 413 478 494 505 498 554 411 33
 Homozygous 83 64 65 62 69 68 81 77 94 76 3
 Frameshift 11 8 8 9 7 8 10 10 14 8 0
 Novel 3 2 4 6 2 3 4 3 7 2 0
Total Gain of Stops 242 125 149 155 158 153 177 246 253 132 30
 Homozygous 72 56 68 76 61 67 73 57 68 60 1
 Novel 10 2 4 6 8 5 10 8 5 1 1