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Table 4 Top 5 overrepresented GO terms within the 6 genes including missense SNVs detected among all of the SAMP strains, but absent in the SAMR and AKR/J strains

From: Exome sequencing of senescence-accelerated mice (SAM) reveals deleterious mutations in degenerative disease-causing genes

GO ID GO category Number of reference genes in the category Number of genes in the gene set and also in the category Expected number in genes in the gene set Raw p-value Adjusted p-value Gene symbol
GO:0006284 base-excision repair 17 2 0.01 1.35×10-5 0.0003 Mbd4, Ogg1
GO:0006281 DNA repair 213 2 0.08 0.0022 0.0202 Mbd4, Ogg1
GO:0006950 response to stress 1107 3 0.39 0.0042 0.0202 Alox5, Mbd4, Ogg1
GO:0034984 cellular response to DNA damage stimulus 243 2 0.09 0.0028 0.0202 Mbd4, Ogg1
GO:0006974 response to DNA damage stimulus 274 2 0.1 0.0036 0.0202 Mbd4, Ogg1