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Table 3 Survival of haploid yeast cells after a single brief exposure to the antitumor drug bleomycin

From: A multistep genomic screen identifies new genes required for repair of DNA double-strand breaks in Saccharomyces cerevisiae

Strain

Gamma

Bleomycin

Fold reduction

 

(60 krad)

(10 ug/ml)

 

WT

R

100 ± 10.7%

 

rad57

SS

0.8 ± 0.3%

125×

rad52

SS

0.04 ± 0.01%

2500×

taf14

R

96.6 ± 28.3%

1.0×

slm4

R

62.8 ± 9.3%

1.6×

nup84

R

13.2 ± 1.2%

7.6×

rem50

R

8.4 ± 2.5%

11.9×

ctf4

R

1.0 ± 0.7

100×

cnm67

S

12.3 ± 2.9%

8.1×

rpb9

SS

6.3 ± 1.1%

15.9×

mms22

S

5.1 ± 2.0%

19.6×

htl1

SS

2.9 ± 0.3%

34.5×

ubr1

SS

2.3 ± 1.0%

43.5×

  1. Averages of four trials and standard deviations are shown.