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Table 4 Cellular functions/processes affected by genes required for resistance to EcoRI

From: A multistep genomic screen identifies new genes required for repair of DNA double-strand breaks in Saccharomyces cerevisiae

Function or process Genes
Sister chromatid cohesion CTF4, CTF8, DCC1, HTL1
Histone modification/remodeling ARP5, EAF1, GCN5, RTT109(REM50)b, SPT10, UBP8
Nuclease processing of DNA EXO1, MMS4, SAE2, YLR235C/TOP3 a
Chromosome stability/segregation BIK1, CGI121, CNM67, DDC1, MMS22
Transcription regulation APQ13/NET1a, BUD32, BUR2, CCR4, NOT5, NUP84, RPB9, BUD30/RPC53a, RTF1, SFP1, SPT20, TAF14, UME6, YML009W-B/SPT5a
RNA processing/modification CDC40, LRP1, LSM7, TRM9, TSR2/YLR434Ca, YDR433W/NPL3a
Protein posttranslational modification AKR1, BCK1, CAX4, MMS2, OCH1, RAD5, UBR1,
  YML012C-A/UBX2 a
Cell membrane/cell wall CIS3, HSP150, RVS161, SAM37, VMA7, VPH2/YKL118W a
Mitochondrial proteins ATP2, IMG2, MCT1, YGL218W/MDM34 a , MRPS35, RSM7/YJR114W a , SCO1
  1. a Gene names separated by a forward slash indicate deletions within two overlapping open reading frames. Functions and processes are described for the verified gene only. Source: The Saccharomyces Genome Database.
  2. b The RTT109 gene is frequently referred to as REM50 in the literature.