Changes in the transcriptome of the malaria parasite Plasmodium falciparumduring the initial phase of transmission from the human to the mosquito

Table 3 Genes identified by SSH with P. berghei orthologs showing destabilization in the absence of DOZI and CITH

P. falciparumgene ID	P	Protein	Predicted feature	MW	P. bergheiortholog gene ID	DOZI	CITH
PF3D7_1011800	74	QF122 antigen	KH domain type 1, RNA binding	131.6	PBANKA_121020	1.4	1.1
PF3D7_0724900	0	kinesin-like protein		222.6	PBANKA_062240	2.4	1.2
PF3D7_1033800	0	plasmepsin VII	SP, 1 TM, aspartyl protease	52.3	PBANKA_051760	2.1	1.3
PF3D7_1316700	0	conserved Plasmodium protein	SP	73.4	PBANKA_141520	2.1	1.4
PF3D7_1321000	0	conserved Plasmodium protein		80.6	PBANKA_141930	1.8	1.6
PF3D7_0303900	19	conserved Plasmodium protein	SP, phosphatidyl-ethanolamine-binding protein PEBP domain	23.2	PBANKA_040250	2.2	1.8
PF3D7_1103500	0	CPW-WPC family protein	SP, CPW-WPC domain	67.3	PBANKA_094340	1.3	2.3
PF3D7_1115200	0	SET domain protein, SET7	Chromatin regulator	94.3	PBANKA_093250	2.5	2.3
PF3D7_1207700	0	blood stage antigen 41–3 precursor	SP	43.4	PBANKA_060620	2.5	2.8
PF3D7_0904200	1	conserved Plasmodium protein	SP, 1 TM	34	PBANKA_041720	1.9	3.2
PF3D7_1362600	0	conserved Plasmodium protein	Interacts with splicing factor 3B subunit 2	32.1	PBANKA_113860	3.4	3.5

P, total number of peptides identified in P. falciparum and P. berghei gametocytes [9, 12, 13, 22]; DOZI and CITH, log₂ values of transcript abundance WT compared to DOZI-KO, or WT compared to CITH KO [20].

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