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Table 2 LCE3C_LCE3B-del and rs4112788G genotype frequencies in 31 world populations

From: Worldwide population distribution of the common LCE3C-LCE3B deletion associated with psoriasis and other autoimmune disorders

Main Geographic Region Populations (ID) Individuals HWE (%) allele frequencies LCE3 C_LCE3B-del SNP genotype frequencies (%) LD
    x2 p-value + AA AG GG r2
Sub-Saharan Africans Pygmies* (PYG) 44 0.93 0.33 64.77 35.23 0 13.64 86.36 0.013
  Mandenka (MAN) 17 0.78 0.56 58.82 41.18 4.55 22.73 72.73 0.121
  Yoruba (YRI) 22 2.18 0.14 65.91 34.09 0 28.57 71.43 0.089
  Bantu (BAN) 18 2.66 0.10 72.22 27.78 0 50.00 50.00 0
North-African/Middle East Mozabite* (ALG) 26 0.04 0.84 32.69 67.31 0 21.43 78.57 0.256
  Bedouin* (BED) 36 0.47 0.49 47.22 52.78 14.63 53.66 31.71 0.772
  Druze* (DRU) 37 1.87 0.17 36.49 63.51 9.09 56.82 34.09 1
  Palestinian (PAL) 40 0.44 0.50 31.25 68.75 4.44 44.44 51.11 0.936
European French (FRA) 27 1.47 0.23 40.74 59.26 16.67 41.67 41.67 1
  French Basque* (BASQ) 21 1.70 0.19 40.48 59.52 9.09 54.55 36.36 0.91
  Sardinian* (SARD) 24 0 0.97 29.17 70.83 13.04 47.83 39.13 1
  Italian (ITL) 17 0.28 0.60 31.76 38.24 35.00 40.00 25.00 1
  Orcadian* (ORC) 16 2.80 0.09 31.25 68.75 23.08 23.08 53.85 1
  Russian (RUS) 23 0.18 0.68 39.13 60.87 14.29 42.86 42.86 0.897
Central-South Asians Brahui (BRA) 22 0.61 0.44 43.18 56.82 21.74 43.48 34.78 1
  Balochi (BAL) 18 0.21 0.65 27.78 72.22 5.00 40.00 55.00 0.852
  Makrani (MAK) 24 0.67 0.41 50.00 50.00 23.81 42.86 33.33 0.55
  Sindhi (SIN) 21 1.71 0.19 33.33 66.67 0 50.00 50.00 0.905
  Kalash* (KAL) 24 1.53 0.22 47.92 52.08 16.67 55.56 27.78 0.861
  Burusho (BUR) 23 3.19 0.07 41.30 58.70 27.27 31.82 40.91 1
  Hazara ( HAZ) 17 1.14 0.29 79.41 20.59 43.75 56.25 0 0.904
Eastern Asians Han (CHB) 34 0 0.98 38.24 61.76 0 52.17 47.83 0.468
  Japanese (JPN) 26 2.45 0.12 48.08 51.92 50.00 37.93 37.93 0.837
  Yaut* (YAK) 11 0.55 0.46 77.27 22.73 50.00 31.82 18.18 1
  NEA 34 0.54 0.46 45.59 54.41 20.59 52.94 26.47 0.852
  SEA 36 0.73 0.40 29.17 70.83 5.88 50.00 44.12 0.537
Oceania Papuan-Melasian (OCE) 35 2.31 0.13 50.00 50.00 26.47 41.18 32.35 0.935
Americans PIMA 22 0.51 0.48 25.00 75.00 9.09 36.36 54.55 0.804
  MAYA 21 0.94 0.33 38.10 61.90 7.14 57.14 35.71 1
  Karitiana (KAR) 17 0.02 0.90 97.06 2.94 90.48 4.76 4.76 1
  Surui* (SUR) 15 1.52 0.22 26.67 73.33 10.53 26.31 63.16 1
  1. *Isolated populations.
  2. Allele and SNP genotype frequencies for all populations analysed, and the r2 value obtained in the linkage disequilibrium analysis.