Skip to main content

Table 2 LCE3C_LCE3B-del and rs4112788G genotype frequencies in 31 world populations

From: Worldwide population distribution of the common LCE3C-LCE3B deletion associated with psoriasis and other autoimmune disorders

Main Geographic Region

Populations (ID)

Individuals

HWE

(%) allele frequencies LCE3 C_LCE3B-del

SNP genotype frequencies (%)

LD

   

x2

p-value

+

AA

AG

GG

r2

Sub-Saharan Africans

Pygmies* (PYG)

44

0.93

0.33

64.77

35.23

0

13.64

86.36

0.013

 

Mandenka (MAN)

17

0.78

0.56

58.82

41.18

4.55

22.73

72.73

0.121

 

Yoruba (YRI)

22

2.18

0.14

65.91

34.09

0

28.57

71.43

0.089

 

Bantu (BAN)

18

2.66

0.10

72.22

27.78

0

50.00

50.00

0

North-African/Middle East

Mozabite* (ALG)

26

0.04

0.84

32.69

67.31

0

21.43

78.57

0.256

 

Bedouin* (BED)

36

0.47

0.49

47.22

52.78

14.63

53.66

31.71

0.772

 

Druze* (DRU)

37

1.87

0.17

36.49

63.51

9.09

56.82

34.09

1

 

Palestinian (PAL)

40

0.44

0.50

31.25

68.75

4.44

44.44

51.11

0.936

European

French (FRA)

27

1.47

0.23

40.74

59.26

16.67

41.67

41.67

1

 

French Basque* (BASQ)

21

1.70

0.19

40.48

59.52

9.09

54.55

36.36

0.91

 

Sardinian* (SARD)

24

0

0.97

29.17

70.83

13.04

47.83

39.13

1

 

Italian (ITL)

17

0.28

0.60

31.76

38.24

35.00

40.00

25.00

1

 

Orcadian* (ORC)

16

2.80

0.09

31.25

68.75

23.08

23.08

53.85

1

 

Russian (RUS)

23

0.18

0.68

39.13

60.87

14.29

42.86

42.86

0.897

Central-South Asians

Brahui (BRA)

22

0.61

0.44

43.18

56.82

21.74

43.48

34.78

1

 

Balochi (BAL)

18

0.21

0.65

27.78

72.22

5.00

40.00

55.00

0.852

 

Makrani (MAK)

24

0.67

0.41

50.00

50.00

23.81

42.86

33.33

0.55

 

Sindhi (SIN)

21

1.71

0.19

33.33

66.67

0

50.00

50.00

0.905

 

Kalash* (KAL)

24

1.53

0.22

47.92

52.08

16.67

55.56

27.78

0.861

 

Burusho (BUR)

23

3.19

0.07

41.30

58.70

27.27

31.82

40.91

1

 

Hazara ( HAZ)

17

1.14

0.29

79.41

20.59

43.75

56.25

0

0.904

Eastern Asians

Han (CHB)

34

0

0.98

38.24

61.76

0

52.17

47.83

0.468

 

Japanese (JPN)

26

2.45

0.12

48.08

51.92

50.00

37.93

37.93

0.837

 

Yaut* (YAK)

11

0.55

0.46

77.27

22.73

50.00

31.82

18.18

1

 

NEA

34

0.54

0.46

45.59

54.41

20.59

52.94

26.47

0.852

 

SEA

36

0.73

0.40

29.17

70.83

5.88

50.00

44.12

0.537

Oceania

Papuan-Melasian (OCE)

35

2.31

0.13

50.00

50.00

26.47

41.18

32.35

0.935

Americans

PIMA

22

0.51

0.48

25.00

75.00

9.09

36.36

54.55

0.804

 

MAYA

21

0.94

0.33

38.10

61.90

7.14

57.14

35.71

1

 

Karitiana (KAR)

17

0.02

0.90

97.06

2.94

90.48

4.76

4.76

1

 

Surui* (SUR)

15

1.52

0.22

26.67

73.33

10.53

26.31

63.16

1

  1. *Isolated populations.
  2. Allele and SNP genotype frequencies for all populations analysed, and the r2 value obtained in the linkage disequilibrium analysis.