Figure 1

Distribution of IGR size in P. falciparum . A) Schematic representing the orientation of divergent, tandem and convergent transcriptional units over IGR types A, B and C, respectively. Block arrows represent the orientation of flanking ORF, transcripts are indicated as dotted lines with the direction of transcription indicated using an arrowhead. Where relevant, the 5′ end of a transcript is indicated with a solid filled dot. For simplicity, only non-overlapping transcriptional units are represented. B) Box and whisker plot representing the distribution of size of IGR types A, B and C. The box represents the 25-75% distribution, the enclosed line the median, with the whiskers indicating the range of sizes between 2.5-97.5% of the entire range. Due to the distribution of data, outliers beyond the 2.5-97.5% of data represented by the range whiskers are not shown. C) Box and whisker plots representing the distribution of the size of IGR types A, B and C in subtelomeric (clear boxes) and chromosomal internal (grey shaded boxes) domains. For each pair of IGR type, the differences are significant (ANOVA, *** p < 0.001). Due to the distribution of data, outliers beyond the 2.5-97.5% of data represented by the range whiskers are not shown.