Figure 4

Overlap between well-positioned nucleosomes in different datasets. A) Each curve shows the average number of reads observed in the indicated dataset within D bp of all well-placed nucleosomes from the Rsa I in vitro assay. B) Same as (A), but with respect to well-placed nucleosomes in the Hinc II in vitro assay. C) Same as (A), but with respect to well-placed nucleosomes in Valouev et al. in vivo dataset [39]. D) Same as (A), but with respect to well-placed nucleosomes in Gu & Fire in vivo dataset [38]. Note that in each panel, the vertical scale of each curve is normalized to match the total read-coverage of the dataset from which the well-placed nucleosomes are drawn. Sequence read cutoffs and filtering procedures used to define well-positioned nucleosomes are described in Methods.