Figure 3
Comparing the methylation status of 10 promoters between NimbleGen HG18 Promoter Array (A) and MeDIP-real time quantitative PCR (B). A, The data of log2(IP/Input) graph shows the methylation signal intensity in the Promoter Array. The bars of upper row and lower row of lo2(IP/Input) graph in each amplifiable promoter fragments denote the methylation signal intensity of each probe in the cfsDNA of PV and Nor, respectively; B, MeDIP-real time quantitative PCR results. Each bar represents the methylation level of amplifiable promoter fragments analyzed by the relative quantity between IP and Input DNA.