Synapomorphic Frequencies Correspond to Conserved Sequences in the Amyloid-β Precursor Protein Gene Family. Histograms of synapomorphic frequency generated for each major branch of the gene family above the representative schematic for each member and the amino acid character map. The colors of the character map were arbitrarily assigned by Mesquite. Lack of a colored line indicates a gap in the aligned sequences. Relevant taxonomic/cladistic classifications are indicated to the left of the maps. (a) APL-1; (b) APPL-1; (c) AbPP; (d) APLP-2; and (e) APLP-1 histograms are binned at 5 residues and scaled as percentages. Descriptions of the schematic regions are found in Figure 1.