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Figure 7 | BMC Genomics

Figure 7

From: Origins of amyloid-β

Figure 7

Amyloid Potential in Vertebrate Amyloid-β Sequence. Plots of probability of aggregation and stabilization of β-fibrils for each amino acid residue from PASTA for representative species. (a) Narke japonica AβPP, (b) Danio rerio AβPP, (c) Homo sapiens AβPP, (d) Mus musculus AβPP, (e) Danio rerio APLP2, (f) Homo sapiens APLP2, (g) Xenopus laevis APLP1, (h) Monodelphis domestica APLP1, and (i) Homo sapiens APLP1. Residues with PASTA energies < − 4 and AmylPred consensus are marked with a black line; residues with PASTA energies between – 3 and – 4 and AmylPred consensus are marked with a grey line.

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