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Table 1 Synapomorphic frequencies within conserved domains

From: Origins of amyloid-β

Domain

Whole tree

APL-1

APPL-1

AβPP

APLP-2

APLP-1

N-Terminal Signal Peptide

11.61

1.25

1.49

2.05

3.31

3.57

E1

14.86

2.71

5.71

3.50

2.43

1.09

E2

18.33

4.95

4.18

3.22

2.83

4.17

E3

6.89

2.44

1.96

0.30

1.19

1.39

  1. APL-1: amyloid precursor like 1 protein; APPL-1: AβPP-like 1 protein; AβPP: amyloid-β precursor protein; APLP-2: amyloid precursor protein like protein 2; APLP-1: amyloid precursor protein like protein 1. This table shows the percentage of synapomorphy accounted for by the N-terminal signal peptide and the three major conserved regions of the peptide sequences for the entire phyologenetic tree and the relative contribution for the five major branches.