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Figure 2 | BMC Genomics

Figure 2

From: Identification of somatic mutations in cancer through Bayesian-based analysis of sequenced genome pairs

Figure 2

Performance of somatic point mutation detection with varying tumor purity. Legend: The sensitivity ( A ) and false discovery rate ( B ) for Seurat, VarScan 2, Strelka and Somaticsniper, given tumor DNA data of varying simulated tumor purity. Seurat reaches 90% sensitivity at ~45% tumor purity in sequence data with average genomic coverage of 128 × .

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