Table 1 Numbers of genes differentially regulated in mab-5 loss- and gain-of-function backgrounds

WT x e1239 lof DOWN

10 (5 in WT x gk670 lof)

38¹ DOWN in LOF combined

WT x gk670 lof DOWN

33

(15 UP in GOF combined)

WT x e1269 lof UP

7 (4 in WT x gk670 lof)

9 UP in LOF combined

WT x gk670 lof UP

6

(1 DOWN in GOF combined)

mab-5 gain-of-function compared to wild type and mab-5 loss-of-function

Combined

WT x e1751 gof DOWN

41 (10 in gk670 lof x e1751 gof)

129¹ DOWN in GOF combined

e1239 lof x e1751 gof DOWN

17 (10 in gk670 lof x e1751 gof)

gk670 lof x e1751 gof DOWN

92 (6 in each)

WT x e1751 gof UP

15 (5 in gk670 lof x e1751 gof)

82 UP in GOF combined

e1239 lof x e1751 gof UP

24 (18 in gk670 lof x e1751 gof)

gk670 lof x e1751 gof UP

65 (3 in each)