Table 7 RNAi of RNA-seq and ChIP-seq candidates
|  | AQR position (%) (n ≥ 100; p ≤ 0.05 compared to mab-5(e1751) | |||||
|---|---|---|---|---|---|---|
Genotype | 1 | 2 | 3 | 4 | 5 | Â |
wild-type | 100 | 0 | 0 | 0 | 0 | Â |
mab-5(e1751) | 0 | 0 | 0 | 8 | 92 | Â |
ceh-20(RNAi) | 89 | 7 | 1 | 3 | 0 | Â |
mab-5(e1751); ceh-20(RNAi) | 0 | 0 | 6 | 35 | 59 | Â |
RNAi in a mab-5 ( e1751 ) background | Â | |||||
Up in mab-5 ( gof ) | Â | Â | Â | Â | Â | Description |
Secreted/transmembrane | Â | Â | Â | Â | Â | Â |
C37C3.6/mig-6 3 | 0 | 0 | 2 | 24 | 74 | Papilin protease inhibitor |
F16C3.2 | 0 | 0 | 1 | 21 | 74 | Secreted |
K02G10.7/aqp-8 | 0 | 0 | 0 | 26 | 74 | aqp-8 aqueporin |
F17E9.11/lys-10 | 0 | 0 | 0 | 23 | 77 | Lysosomal protein |
C35D10.1 1 | 0 | 0 | 0 | 22 | 78 | Transmembrane DUF2012 |
C02A12.4/lys-7 | 0 | 0 | 1 | 20 | 79 | Lysosomal protein |
F11C7.5/osm-11 | 0 | 0 | 0 | 21 | 79 | Secreted |
F10E7.4/spon-1 | 0 | 0 | 0 | 20 | 80 | F-spondin |
C37A5.4/fipr-23 | 0 | 0 | 1 | 16 | 83 | Fungal-induced, secreted |
Gene expression | Â | Â | Â | Â | Â | Â |
C08C3.2/bath-15 | 0 | 0 | 0 | 28 | 67 | BTB-MATH |
C08C3.3/mab-5 2 | 0 | 0 | 1 | 22 | 77 | Hox |
F26D12.1/fkh-7 3 | 0 | 0 | 1 | 18 | 81 | Forkhead |
Cytoplasmic signaling/cytoskeleton | Â | Â | Â | Â | Â | Â |
K08F8.1 1,2 | 0 | 0 | 1 | 24 | 75 | MAPKAP3-like |
T04H1.9/tbb-6 | 0 | 0 | 0 | 21 | 76 | Beta tubulin |
T07C4.9/nex-2 | 0 | 0 | 0 | 23 | 77 | Annexin |
Y17G7B.14/arrd-8 | 0 | 0 | 0 | 20 | 80 | Arrestin |
F59A1.9 | 0 | 0 | 0 | 20 | 80 | F-box containing |
M60.7 | 0 | 0 | 1 | 17 | 82 | Ankyrin-repeat containing |
Metabolism | Â | Â | Â | Â | Â | Â |
C53A3.2 1 | 0 | 0 | 0 | 25 | 75 | Nitrophenylphosphatase |
Down in mab-5 ( lof ) | Â | Â | Â | Â | Â | Â |
ZC443.6/ugt-16 | 0 | 0 | 0 | 22 | 78 | UDP Glucuronosyltransferase |
W10G11.1 | 0 | 0 | 1 | 18 | 81 | Secreted cys-rich DUF19 |
F48C1.8 | 0 | 0 | 0 | 19 | 81 | Secreted, conserved |
ChIP seq targets | Â | Â | Â | Â | Â | Â |
T23G4.2 | 0 | 0 | 0 | 38 | 62 | Unsimilar cytoplasmic |
T24D1.4/tag-179 | 0 | 0 | 0 | 33 | 67 | Transmembrane glycosyltransferase ALG10 |
C55B7.7/gly-2 | 0 | 0 | 0 | 33 | 67 | Secreted glycosyltransferase, family 18 |
T23G4.1/tlp-1 | 0 | 0 | 0 | 30 | 70 | Zinc-finger transcription factor |
F22D6.2 | 0 | 0 | 0 | 29 | 71 | AN1-like zinc finger |
F54F2.2/zfp-1 | 0 | 0 | 0 | 27 | 73 | Zinc finger PHD-like |
F32E10.1/nol-10 | 0 | 0 | 0 | 26 | 74 | Nucleolar protein |
M05B5.4 | 0 | 0 | 1 | 23 | 76 | Phospholipase A2-like |
R13A5.5/ceh-13 | 0 | 0 | 0 | 24 | 76 | Hox-B1/Labial |
W09G12.8 | 0 | 0 | 0 | 24 | 76 | Peptide N-glycanase/PAW domain |
F33G12.6 | 0 | 0 | 0 | 24 | 76 | Protein phosphatase 2C-like |
R01E6.3/cah-4 | 0 | 0 | 0 | 24 | 78 | Carbonic anhydrase |
B0361.2 | 0 | 0 | 0 | 21 | 79 | CwfJ C-terminal domains |
F42C5.9 | 0 | 0 | 0 | 20 | 80 | Actin-like PH domain |
F21A10.2 | 0 | 0 | 0 | 20 | 81 | Transmembrane myelin regulatory factor |
DY3.2/lmn-1 | 0 | 0 | 0 | 19 | 81 | Nuclear lamin |
C09H6.3/mau-2 | 0 | 0 | 0 | 19 | 81 | Chromatid cohesion factor |