Fate of the human Y chromosome linked genes and loci in prostate cancer cell lines DU145 and LNCaP

Yadav, Sandeep Kumar; Kumari, Anju; Ali, Sher

doi:10.1186/1471-2164-14-323

BMC Genomics

Table 1 List of STSs analyzed to ascertain the genetic integrity of the Y-chromosome in the prostate cancer cell lines DU145 and LNCaP

From: Fate of the human Y chromosome linked genes and loci in prostate cancer cell lines DU145 and LNCaP

Serial No.	STS Identifier	Location	Multi-Copy	STS Status in DU145	STS status in LNCaP
1	sY14	SRY exon 1		+	+
2	sY1240	PCDH11Y intron 3		+	+
3	sY276	AMELY exon 4/intron 4		+	+
4	sY1238	TBL1Y exon 11		+	+
5	sY637	PRKY 5’ upstream of gene		+	+
6	sY1319	PRKY 3’ UTR		+	+
7	sY1250	Proximal boundary of TSPY array		+	+
8	sY78	Alpha satellite (DYZ3) sequences in centromeric region	*	+	+
9	sY1251	Boundary between centromere and Yq		+	+
10	sY1317	USP9Y exon 3		+	+
11	sY1316	USP9Y exon 26		+	+
12	sY1234	DDX3Y (DBY) exon 9		+	+
13	sY1231	UTY exon 8		+	+
14	sY1235	XKRY exon 1	*	+	+
15	sY1260	CDY2 exon 1	*	+	+
16	sY1237	HSFY exon 2	*	+	+
17	sY121	Immediately distal to palindrome P4		+	+
18	sY1322	Between CYorf15A & CYorf15B		+	+
19	sY280	JARID1D (SMCY) exon 9/intron 9		+	+
20	sY1233	EIF1AY exon 1		+	+
21	sY1682	RPS4Y2 exon 1		+	+
22	sY627	RBMY1 exon 12	*	+	+
23	sY1258	Boundary between unique sequence u1 & blue amplicon b1 in AZFc		+	+
24	sY1161	PRY intron 2	*	+	+
25	sY1197	Internal boundary of Palindrome P3		+	+
26	sY1191	Unique sequence u3 in AZFc		+	+
27	sY1035	BPY2 intron 5	*	+	+
28	sY1318	DAZ exon 11	*	+	+
29	sY254	DAZ exon 3	*	+	+
30	sY1291	Red/gray boundary in AZFc		+	+
31	sY1125	Blue/gray boundary in AZFc	*	+	+
32	sY1054	Blue/yellow boundary in AZFc	*	+	+
33	sY1190	Yellow amplicon in AZFc	*	+	+
34	sY1263	CDY1 exon 1/intron 1	*	+	+
35	sY1206	Yellow/green boundaries in AZFc	*	+	+
36	sY1201	Distal boundary of gray amplicon in AZFc		+	+
37	sY1256	TSPY intron 5	*	+	+
38	sY1247	Boundary between PAR1 and MSY		+	+
39	sY1230	TMSB4Y exon 1/intron 1		+	+
40	sY1166	In MSY between distal Yq heterochromatin & PAR2		+	+
41	sY274	RPS4Y1 intron 4		+	+
42	sY1220	VCY exon 2	*	+	+
43	sY90	KALP intron 1		+	+
44	sY210	STSP intron 5		+	+
45	sY1254	TGIF2LY exon 1		+	+
46	sY1239	NLGN4Y exon 1		+	+
47	sY1273	Near boundary between MSY & PAR2		+	+
48	sY238	ZFY intron 2		+	+
49	sY1246	Proximal portion of distal Yq heterochromatin		+	+
50	sY142	Proximal to AZFc		+	+
51	sY160	Satellite-3 (DYZ1) sequences in distal Yq heterochromatin	*	+	+

Multi-copy STSs are indicated by star (*) and plus (+) sign denotes the presence of a particular STS.

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ISSN: 1471-2164

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