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Table 2 List of all pathways where Sens-alus and Ant-alus are enriched or depleted

From: A gene expression restriction network mediated by sense and antisense Alu sequences located on protein-coding messenger RNAs

Pathway

Ant-alu P

Sens-alu P

Ant-alu enriched

  

p53 pathway

0.0005†

0.2470

Opioid prodynorphin pathway

0.0015†

0.6090

Muscarinic acetylcholine receptor 2 and 4 signaling pathway

0.0018†

0.2270

Pyridoxal phosphate salvage pathway

0.0023†

0.9260

Vitamin B6 metabolism

0.0050†

0.8910

Metabotropic glutamate receptor group II pathway

0.0070†

0.5520

5HT1 type receptor mediated signaling pathway

0.0077†

0.2930

Opioid proopiomelanocortin pathway

0.0088†

0.4040

Opioid proenkephalin pathway

0.0088†

0.4040

Endogenous_cannabinoid_signaling

0.0132†

0.3670

GABA-B_receptor_II_signaling

0.0133†

0.4560

Metabotropic glutamate receptor group III pathway

0.0144†

0.5340

Muscarinic acetylcholine receptor 1 and 3 signaling pathway

0.0189†

0.3270

Beta3 adrenergic receptor signaling pathway

0.0210†

0.3220

Cortocotropin releasing factor receptor signaling pathway

0.0312

0.3770

5HT4 type receptor mediated signaling pathway

0.0341

0.1540

Synaptic_vesicle_trafficking

0.0372

0.5960

p53 pathway feedback loops 2

0.0407

0.1580

Angiotensin II-stimulated signaling through G proteins and beta-arrestin

0.0438

0.5690

Ant-alu depleted

  

Huntington disease

0.0230

0.3950

Sens-alu enriched

  

Toll receptor signaling pathway

0.6120

0.0042

DPP_signaling_pathway

0.5960

0.0210

Nicotinic acetylcholine receptor signaling pathway

0.2970

0.0225

Gamma-aminobutyric acid synthesis

0.8130

0.0229

SCW_signaling_pathway

0.4430

0.0289

BMP_signaling_pathway-drosophila

0.4430

0.0289

Interleukin signaling pathway

0.5740

0.0365

Endothelin signaling pathway

0.3140

0.0420

DPP-SCW_signaling_pathway

0.5150

0.0487

  1. †The accompanying False Discover Rate < 25%.
  2. The P values were nominal values without being corrected for multiple comparisons.