Skip to main content

Table 2 Greater pig-human similarity revealed by gene family analysis

From: Structural and functional annotation of the porcine immunome

Family description (SF: superfamily)

Number of genes found for each family per species*

 

Human

Mouse

Cow

Pig

ADP-ribosyltransferase/VIP2 SF

4

5 (1)

9

4

Beta Defensin SF

39 (9)

51 (1)

~106 (7)

34 (2)

BPI SF

12 (2)

16

18

14 (2)

C-type Lysozyme/LYZ1 SF

9

9

16

7

Cathelicidin SF

1

1

10

10

CCL Chemokine

28 (1)

39 (5)

22

21

CD1 SF

5

2

15 (2)

4 (1)

CD163/WC1 SF

3

4

15

4

CLECT SF (inclusive)

85 (3)

126 (6)

89

76

CLECT SF, AGP and DCR Subfamily

16

24 (1)

14

13

CLECT SF, Collectin Subfamily

7 (2)

7

10

7

CLECT SF, NK Cell Receptor Subfamily

24 (1)

57 (5)

31

23

CLECT SF, Reg Subfamily

5

7

3

3

Cytidine Deaminase-like SF

11 (0)

5 (0)

6 (0)

5 (0)

GH18 Chitinase Like SF

6 (1)

9 (1)

8

7

Granzyme/ MC Tryptase/SP SF

17 (1)

26 (0)

22 (0)

18 (0)

Immunity Related GTP-ase SF

3 (2)

19 (4)

4 (0)

4 (0)

NLR and Pyrin SF

31 (4)

43 (8)

23

25

Resistin SF

2

4

1

2

RNase A Family

14

22 (6)

16 (1)

13 (1)

S100 SF

21

17 (1)

19

20

SAA SF

4 (1)

5

6

6

SLAM SF

9 (1)

9 (0)

12 (0)

11 (0)

Toll Like Receptor

10 (3)

12 (1)

10

10 (2)

TRIM E3 Up Ligase SF, TRIM5 Subfamily

4

10 (1)

5

3

Type I Interferon (inclusive)

17 (12)

25 (2)

51 (13)

39 (16)

Type I Interferon, Alpha Subfamily

13 (4)

13 (1)

19 (3)

18 (9)

Type I Interferon, Beta Subfamily

1

1

8 (1)

1

Type I Interferon, Delta Subfamily

0

0

0

11 (2)

Type I Interferon, Epsilon Subfamily

1

1

0

1

Type I Interferon, Kappa Subfamily

1

1

1

1

Type I Interferon, Omega Subfamily

1 (8)

0

19 (7)

7 (5)

Type I Interferon, Tau Subfamily

0

0

4 (2)

0

Type I Interferon, Zeta Subfamily

0

9 (1)

0

0

ULBP SF

6

2

12

7

  1. * Numbers of confirmed pseudogenes are shown in parentheses. AGP and DCR: Asialo- glycoprotein and DC Receptor; MC: Mast Cell; SP: Serine Protease; Up: Ubiquitin-protein.