Figure 3

False positive distribution for PSP (A) and PDS (B). Co-localisation and expression profile of PDSs and complexes (DNA synthesome and TNF-alpha/NF-kappa B signaling complex 5) on the purine metabolism pathway. A: The purine metabolic pathway is shown as an undirected graph. Significant PSP clusters are highlighted in green while significant PDS is shown in purple. B and C: Regression plots for expression scores of protein complexes and PDSs co-located on the same biological pathway in mod and poor stage respectively. Enveloped in a checked circle are two complex outliers that are low expressing in the mod stage relative to the co-locating PDS but swung to overexpression in the poor stage