Table 2 Sequence quality and closest HLA allele designation for heterozygous samples
From: Phase-defined complete sequencing of the HLA genes by next-generation sequencing
Sample | Gene | Average depth | Coverage¶(allele 1/allele 2) | Luminex genotype | Closest HLA genotype |
|---|---|---|---|---|---|
E1 | A | 4306.6 | 97.1/100 | 02:01/31:01 | 02:01:01:01/31:01:02 |
| Â | C | 6668.5 | 100/99.6 | 03:03/03:04 | 03:03:01/03:04:01:01 |
| Â | B | 5250.9 | 100/100 | 15:11/40:01 | 15:11:01 * /40:01:02 |
| Â | DRB1 | 272.2 | 99.7/95.6 | 04:05/09:01 | 04:05:01/09:01:02 * |
| Â | DQB1 | 3322.3 | 100/99.5 | 03:03/04:01 | 03:03:02:02/04:01:01 |
| Â | DPB1 | 780.8 | 95.5/100 | 02:02/05:01 | 02:02/05:01:01 * |
E8 | A | 4303.7 | 100†| 24:02/24:02 | 24:02:01:01/24:02:01:01 |
| Â | C | 3904.7 | 100/100 | 12:02/14:02 | 12:02:02/14:02:01 |
| Â | B | 2829.4 | 99.7/100 | 51:01/52:01 | 51:01:01/52:01:01:01 |
| Â | DRB1 | 612.3 | 100/100 | 01:01/15:02 | 01:01:01/15:02:01 |
| Â | DQB1 | 3132.6 | 100/100 | 05:01/06:01 | 05:01:01:02/06:01:01 |
| Â | DPB1 | 588.7 | 100/100 | 04:02/09:01 | 04:02:01:02/09:01 |
E11 | A | 3880.2 | 100/100 | 24:02/31:01 | 24:02:01:01/31:01:02 |
| Â | C | 3695.0 | 100/100 | 01:02/07:04 | 01:02:01/07:04:01 |
| Â | B | 4490.7 | 100/100 | 15:18/54:01 | 15:18:01 * /54:01:01 |
| Â | DRB1 | 501.8 | 78.3/99.2 | 04:01/04:05 | 04:01:01/04:05:01 |
| Â | DQB1 | 3751.8 | 100/100 | 03:01/04:01 | 03:01:01:01/04:01:01 * |
| Â | DPB1 | 748.2 | 100/100 | 02:01/05:01 | 02:01:02 * /05:01:01 * |
E17 | A | 808.4 | 100/100 | 02:07/24:02 | 02:07:01/24:02:01:01 |
| Â | C | 1708.7 | 100/100 | 01:02/12:02 | 01:02:01/12:02:02 |
| Â | B | 2507.7 | 100/100 | 46:01/52:01 | 46:01:01/52:01:01:02 |
| Â | DRB1 | 2080.3 | 100/100 | 08:03/15:02 | 08:03:02/15:02:01 |
|  | DQB1 | 1638.1 | 100†| 06:01/06:01 | 06:01:01/06:01:01 |
| Â | DPB1 | 1649.6 | 97.9/98.4 | 05:01/09:01 | 05:01:01 * /09:01 |
E25 | A | 1042.7 | 100/100 | 02:06/24:02 | 02:06:01/24:02:01:01 |
| Â | C | 2150.0 | 100/100 | 07:02/12:02 | 07:02:01:03/12:02:02 |
| Â | B | 4871.7 | 100/100 | 07:02/52:01 | 07:02:01/52:01:01:02 |
| Â | DRB1 | 460.3 | 100/32.8 | 01:01/09:01 | 01:01:01 * /09:01:02 * |
| Â | DQB1 | 1396.3 | 100/100 | 03:03/05:01 | 03:03:02:02/05:01:01:02 * |
| Â | DPB1 | 2289.0 | 99.6/100 | 02:02/04:02 | 02:02 * /04:02:01:01 * |
E28 | A | 1645.3 | 97.2/100 | 26:01/33:03 | 26:01:01/33:03:01 * |
|  | C | 824.8 | 99.7†| 03:04/03:04 | 03:04:01:02/03:04:01:02 |
| Â | B | 2799.6 | 100/100 | 40:02/40:06 | 40:02:01 * /40:06:01:01 |
|  | DRB1 | 236.5 | 100†| 09:01/09:01 | 09:01:02 * /09:01:02 * |
|  | DQB1 | 817.5 | 100†| 03:03/03:03 | 03:03:02:02/03:03:02:02 |
|  | DPB1 | 343.0 | 100†| 02:01/02:01 | 02:01:02/02:01:02 |
E30 | A | 1711.4 | 100/100 | 24:02/33:03 | 24:02:01:01/33:03:01 * |
| Â | C | 2670.8 | 100/100 | 01:02/14:03 | 01:02:01 * /14:03 |
| Â | B | 1899.1 | 100/100 | 44:03/55:02 | 44:03:01/55:02:01 |
| Â | DRB1 | 399.4 | 17.1/99.8 | 09:01/13:02 | 09:01:02 * /13:02:01 * |
| Â | DQB1 | 773.1 | 100/97.8 | 03:03/06:04 | 03:03:02:02/06:09 * |
| Â | DPB1 | 460.4 | 100/100 | 04:01/04:01 | 04:01:01/04:01:01 |
M13 | A | 3689.7 | 97.2/100 | 11:01/24:02 | 11:01:01/24:02:01:01 |
| Â | C | 3386.3 | 100/100 | 01:02/04:01 | 01:02:01/04:01:01:01 |
| Â | B | 3508.5 | 100/100 | 15:01/59:01 | 15:01:01:01/59:01:01:01 |
| Â | DRB1 | 1029.3 | 100/99.5 | 04:05/09:01 | 04:05:01/09:01:02 * |
| Â | DQB1 | 577.6 | 100/100 | 03:03/04:01 | 03:03:02:02/4:01:01 |
| Â | DPB1 | 1981.8 | 100/100 | 04:02/05:01 | 04:02:01:02/05:01:01 * |
M14 | A | 1690.3 | 100/100 | 31:01/33:03 | 31:01:02/33:03:01 |
| Â | C | 4353.2 | 100/100 | 04:01/06:02 | 04:01:01:01/06:02:01:01 |
| Â | B | 4733.5 | 100/100 | 15:01/57:01 | 15:01:01:01/57:01:01 |
| Â | DRB1 | 446.2 | 100/99.5 | 15:01/07:01 | 15:01:01:02*/07:01:01 |
| Â | DQB1 | 763.0 | 98.8/98.9 | 03:03/06:02 | 03:03:02:01/06:02:01 |
| Â | DPB1 | 1209.5 | 99.8/100 | 09:01/04:02 | 09:01/04:02:01:02 * |
M15 | A | 1153.2 | 100/100 | 31:01/33:03 | 31:01:02/33:03:01 |
| Â | C | 1448.1 | 99.7/99.8 | 14:02/14:03 | 14:02:01/14:03 |
| Â | B | 3312.9 | 100/100 | 44:03/51:01 | 44:03:01/51:01:01 |
|  | DRB1 | 463.4 | 100†| 04:05/04:05 | 04:05:01/04:05:01 |
|  | DQB1 | 280.9 | 100†| 04:01/04:01 | 04:01:01 * /04:01:01 * |
| Â | DPB1 | 2932.9 | 99.5/100 | 02:01/03:01 | 02:01:02/03:01:01 |
M20 | A | 7631.1 | 100/100 | 02:06/11:01 | 02:06:01/11:01:01 |
| Â | C | 7675.7 | 100/100 | 03:03/08:01 | 03:03:01/08:01:01 |
| Â | B | 7566.7 | 100/100 | 15:02/35:01 | 15:02:01/35:01:01:01 * |
|  | DRB1 | 4746.2 | 100†| 15:01/15:01 | 15:01:01:01/15:01:01:01 |
| Â | DQB1 | 6952.9 | 100/100 | 06:01/06:02 | 06:01:01/06:02:01 |
| Â | DPB1 | 4631.3 | 100/99.6 | 05:01/02:02 | 05:01:02/02:02 |