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Table 3 Quantitative trait loci identified for sex, yield and cone chemistry traits in hop, in (a) a New Zealand mapping population and (b) a Slovenian mapping population

From: Quantitative trait loci in hop (Humulus lupulusL.) reveal complex genetic architecture underlying variation in sex, yield and cone chemistry

Chemical group Trait QTL Linkage group Seg. a Adjacent marker Position (cM) LOD b % exp c Additive d Kruskal-Wallis
a.            
hop acid α-acid α-acid α-acid-1 Nugget 1 F D-hPb-718465-l-4af 0.0 2.91 8.6 0.43 P < 0.0005
α-acid-2 Nugget 5 F D-hPb-618369-l-1f 34.4 2.62 7.1 0.40 P < 0.0005
humulone + adhumulone humulone + adhumulone-1 Nugget 5 F D-hPb-618369-l-1f 34.4 4.26 11.3 0.39 P < 0.0001
humulone + adhumulone-3 Nugget 1 F D-hPb-718465-l-4af 0.0 2.58 6.7 0.29 P < 0.001
cohumulone cohumulone-1 Nugget 2 F D-hPb-364480-l-4c*f 1.8 8.14 21.9 −0.21 P < 0.0001
cohumulone-2 Nugget 1 F D-hPb-718465-l-4af 0.0 3.29 8.1 0.12 P < 0.0005
cohumulone (% of α-acid) cohumulone (% of α-acid)-1 Nugget 2 F S-GT4-J12-15-lf 3.5 24.78 43 −2.78 P < 0.0001
β-acid β-acid β-acid −1 Nugget 5 F D-hPb-366221-l-1f 39.0 5.01 11.9 0.23 P < 0.0001
β-acid −2 Nugget 2 F D-hPb-364480-l-4c*f 1.8 5.01 11.9 −0.23 P < 0.0005
β-acid −3 S.B.L. 3/3 3 M S-HLGT14*-n*m 0.0 4.39 10.3 −0.28 P < 0.05
β-acid-4 Nugget 8 F D-hPb-362051-l-4af 5.9 2.37 5.4 0.15 P < 0.05
lupulone + adlupulone lupulone + adlupulone-1 Nugget 5 F D-hPb-366221-l-1f 39.0 5.72 14.7 0.13 P < 0.0001
lupulone + adlupulone-2 S.B.L. 3/3 3 M S-HLGT14*-n*m 0.0 3.70 9.2 −0.13 P < 0.005
lupulone + adlupulone-3 Nugget 8 F D-hPb-362051-l-4af 5.9 3.17 7.8 0.09 P < 0.005
colupulone colupulone-1 Nugget 2 F D-hPb-364480-l-4c*f 1.8 8.40 21.8 −0.16 P < 0.0001
colupulone-2 Nugget 5 F D-hPb-366221-l-1f 39.0 3.55 8.5 0.10 P < 0.0005
colupulone (% of β-acid) colupulone (% of β-acid)-1 Nugget 2 F D-hPb-719407-l-4af 2.8 20.54 44.4 −2.4 P < 0.0001
ratio α-acid:β-acid α-acid:β-acid-1 Nugget 8 F D-hPb-362051-l-4af 5.9 4.44 10.5 −0.15 P < 0.0005
α-acid:β-acid-2 Nugget 2 F D-hPb-364957-l-4af 2.3 4.40 10.4 0.15 P < 0.0005
α-acid:β-acid-3 S.B.L. 3/3 3 M D-hPb-716654-n-1 m 36.2 3.63 8.5 0.13 P < 0.001
α-acid:β-acid-4 Nugget 1 F D-hPb-716855-l-4af 29.5 2.65 6.1 0.11 P < 0.01
essential oil ester methyl decanoate methyl decanoate-1 Nugget 2 F D-hPb-364957-l-4af 2.3 6.91 17.2 0.04 P < 0.0001
methyl decanoate-2 S.B.L. 3/3 3 M D-hPb-716654-n-1 m 36.2 3.70 8.7 −0.03 P < 0.0001
methyl decanoate-3 Nugget 1 F D-hPb-366735-l-1*f 0.0 2.45 5.6 −0.03 P < 0.001
methyl dec-4-enoate methyl dec-4-enoate-2 Nugget 1 F D-hPb-366735-l-1*f 0.0 3.81 12.3 0.21 P < 0.0001
methyl-4-methylhex-2-enoate methyl-4-methylhex-2-enoate-2 Nugget 5 F S-AP20_600-lf 50.4 2.36 6.1 0.07 P < 0.01
ketone 2-undecanone 2-undecanone-1 S.B.L. 3/3 3 M D-hPb-716654-n-1 m 36.2 25.1 53.8 0.14 P < 0.0001
2-undecanone-2 Nugget 5 F S-AP20_600-lf 50.4 4.62 6.8 −0.05 P < 0.01
ether humulene diepoxide a humulene diepoxide a-1 Nugget 2 F S-GA8-K15-4-lf 2.4 2.37 7.8 0.11 P < 0.05
monoterpene alcohol linalool linalool-1 Nugget 5 F D-hPb-618369-l-1f 34.4 2.68 8.8 0.06 P < 0.005
sesquiterpene alcohol humulol humulol-1 Nugget 2 F D-hPb-364957-l-4af 2.3 3.81 11.2 0.04 P < 0.0001
humulol-2 S.B.L. 3/3 3 M D-hPb-716654-n-1 m 36.2 2.80 8.1 −0.03 P < 0.0005
t-cadinol t-cadinol-1 S.B.L. 3/3 3 M D-hPb-716654-n-1 m 36.2 3.34 10.1 −0.03 P < 0.0005
monoterpene β-pinene β-pinene-1 Nugget 2 F D-hPb-364957-l-4af 2.3 5.42 16.1 −0.07 P < 0.0001
limonene limonene-1 S.B.L. 3/3 3 M S-HLGT14*-n* 0.0 2.33 7.7 −0.17 P < 0.001
myrcene myrcene-1 Nugget 2 F D-hPb-364957-l-4af 2.3 5.54 16 −5.61 P < 0.0001
myrcene-2 Nugget 5 F D-hPb-618369-l-1f 34.4 3.56 9.9 4.43 P < 0.005
ρ-cymene ρ-cymene-1 Nugget 5 F D-hPb-362315-l-1f 44.5 2.84 9.3 0.04 P < 0.0005
terpinene terpinene-1 S.B.L. 3/3 6 M D-hPb-619280-n-1*m 14.2 3.19 9.3 0.14 P < 0.0001
terpinene-2 Nugget 2 F D-hPb-719075-l-4a*f 0.0 2.73 7.9 −0.13 P < 0.0001
sesquiterpene α-capaene α-capaene-1 S.B.L. 3/3 3 M D-hPb-619412-n-1 m 35.1 3.52 11.4 −0.05 P < 0.0005
α-selinene α-selinene-1 Nugget 1 F D-hPb-718465-l-4af 0.0 4.01 12.9 −0.19 P < 0.0001
β-selinene β-selinene-1 Nugget 2 F D-hPb-364957-l-4af 2.3 3.88 11.5 0.07 P < 0.0001
δ-cadinene δ-cadinene-1 Nugget 1 F D-hPb-618333-l-1f 45.2 6.05 18.8 0.23 P < 0.0001
γ-cadinene γ-cadinene-1 Nugget 1 F D-hPb-618333-l-1f 45.2 7.87 22.6 0.41 P < 0.0001
γ-cadinene-2 S.B.L. 3/3 3 M D-hPb-716654-n-1 m 36.2 2.67 7 −0.23 P < 0.05
caryophyllene caryophyllene-1 S.B.L. 3/3 3 M D-hPb-716654-n-1 m 36.2 6.23 13.7 −1.45 P < 0.0001
caryophyllene-2 Nugget 1 F D-hPb-715569-l-1 28.3 5.45 12.6 1.39 P < 0.005
caryophyllene-3 Nugget 2 F D-hPb-364957-l-4af 2.3 5.10 11 1.32 P < 0.0001
farnesene farnesene-1 S.B.L. 3/3 3 M D-hPb-716654-n-1 m 36.2 39.78 71.3 6.45 P < 0.0001
farnesene-2 Nugget 5 F S-AP20_600-lf 50.4 4.62 4.2 −1.62 P < 0.05
humulene humulene-1 Nugget 1 F D-hPb-362665-l-1f 39.3 7.15 15.3 −3.67 P < 0.0001
humulene-2 S.B.L. 3/3 3 M D-hPb-716654-n-1 m 36.2 6.42 13.8 −3.45 P < 0.0001
humulene-3 Nugget 2 F D-hPb-719075-l-4a*f 0.0 3.61 7.3 2.55 P < 0.01
humulene-4 Nugget 5 F D-hPb-618369-l-1f 34.4 2.66 5.3 −2.22 P < 0.005
muurolene muurolene-1 S.B.L. 3/3 3 M D-hPb-716654-n-1 m 36.2 8.83 22.6 −0.15 P < 0.0001
muurolene-2 Nugget 2 F D-hPb-364957-l-4af 2.3 5.17 12.4 0.11 P < 0.0001
ratio humulene:caryophyllene humulene:caryophyllene-1 Nugget 1 F D-hPb-362665-l-1f 39.3 38.44 66.9 −0.54 P < 0.0001
poly-phenol poly-phenol xanthohumol xanthohumol-1 Nugget 2 F D-hPb-364957-l-4af 2.3 11.5 29.5 −0.05 P < 0.0001
xanthohumol-2 Nugget 1 F D-hPb-715569-l-1f 28.3 2.46 5.4 −0.02 P < 0.01
yield secondary metabolites essential oil content essential oil content-1 Nugget 2 F D-hPb-364957-l-4af 2.3 6.66 20.1 −0.16 P < 0.0001
sex sex sex sex-1 S.B.L. 3/3 5 M S-HLAGA7-a*m 2.1 13.84 22.6 −0.28 P < 0.0001
b.            
yield cone dry cone weight dry cone weight-1 Hallertauer Magnum 1 F D-hPb-716855-l-4a*f 16.0 7.49 35.0 0.05 P < 0.0001
sex sex sex sex-1 S.B.L. 2/1 5 M S-HLAGA7-e* 20.5 1441.23 81 0.50 P < 0.0001
  1. a Seg. indicates the segregation of the QTL from either the maternal (F) or paternal (M) parent.
  2. b LOD indicates the peak LOD score for the QTL at the genome-wide significance level.
  3. c % exp. indicates the percentage of the phenotypic variation of the trait explained by the QTL.
  4. d Additive indicates the estimated additive effect of the allele (i.e. (mean of the distribution of the quantitative trait associated with the female genotype – mean of the distribution of the quantitative trait associated with the male genotype)/2.