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Table 3 Sensitivity benchmarking statistics

From: Sensitive and specific detection of mosaic chromosomal abnormalities using the Parent-of-Origin-based Detection (POD) method

  triPOD paired BAFseg PSCN genoCNA MAD PennCNV joint
Mean detection threshold 0.96 0.81 0.82 0.71 0.78 NA
Proportion detected >= 95% 0.91 0.78 0.79 0.69 0.37 0.31
Mean Region Size (SNPs) 6874 4481 376 579 705 246
  1. Detection statistics are compared between triPOD and other benchmarked programs. The mean detection threshold is the mean of the percent normal cells (> 50%) at which the sensitivity of detection first drops to zero. The proportion detected >= 95% refers to the proportion of the total number of simulated abnormalities detected with >= 95% sensitivity. The mean region size serves as an indication of a program’s ability to call an entire abnormality as a single abnormal region.