IPA transcription factor analysis. Each coloured node represents a gene; Red: upregulated genes. Green: downregulated genes. White open nodes represent Transcription factors. A solid line denotes a direct functional interaction of the transcription factor on the genes. A dotted line denotes an indirect interaction. (A) 15 min upstream analysis results (B) 2 h upstream analysis results (C) 24 h, upstream analysis results, up-regulated genes only.