Gene symbol | Gene title | Fold change | Functional effects | References | ||
---|---|---|---|---|---|---|
 |  | 15 min | 2 h | 24 h |  |  |
Fish | Adapter protein TKS5 | 1.2 | - | - | Mediates the neurotoxic effect of amyloid-β | [35] |
Frp2 | Formyl peptide receptor 2 | - | - | −1.4 | Activated by amyloid-β, may mediate inflammation seen in Alzheimer's disease | [36] |
Gapdh | Glyceraldehyde-3-phosphate dehydrogenase | 1.2 | - | −1.5 | May interact with neurodegenerative disease-associated proteins | [37] |
Ppif | Peptidylprolyl isomerase F | - | - | −1.4 | An absence of this gene is neuroprotective against amyloid-β induced cell death | [38] |
Tnf | Tumour necrosis factor | 1.4 | - | - | Protects neurons against amyloid-β induced toxicity | [39] |
Ttr | Transthyretin | - | −2.8 | - | Binds amyloid-β and prevents fibril formation in vitro | [40] |
Ccl-3 | Chemokine (C-C motif) ligand 3 | - | 1.3 | - | Protein levels are increased in Alzheimer's disease | [41] |
Fos | FBJ murine osteosarcoma viral oncogene homolog | 1.3 | - | - | Gene expression is increased in Alzheimer's disease | [42] |
Ilib | Interleulin 1-beta | - | 1.3 | - | Protein levels are increased in Alzheimer's disease | [43] |
MiR-9 | MicroRNA- 9 | 1.2 | −1.2 | - | Expression is reduced in Alzheimer's disease | [44] |
MiR-29 | MicroRNA-29 | 1.3 | - | - | Regulator of BACE1 and decreased in Alzheimer's disease | [45] |
Otc | Ornithine transcarbamylase | −1.2 | - | - | Gene expression is increased in Alzheimer's disease | [46] |
Rgsl2 | Regulator of G-protein signaling like 2 | - | 1.2 | - | Gene associated with late onset Alzheimer's disease | [47] |