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Table 2 Differentially expressed genes induced by bleomycin in lung tissues of Fra-1 +/+ and Fra-1 ∆/∆ mice

From: Expression profiling of genes regulated by Fra-1/AP-1 transcription factor during bleomycin-induced pulmonary fibrosis

Affymetrix ID Symbol Gene title KOT vs. WTT (fold change)
Cytokine, chemokines, and their receptors    
 10531415 Cxcl10 C-X-C motif chemokine 10 2.54
 10379535 Ccl8 Chemokine (C-C motif) ligand 8 2.27
 10520452 Il6 Interleukin 6 2.23
 10469278 Il2ra Interleukin-2 receptor alpha chain 2.15
 10487588 Il1a Interleukin-1 alpha 1.87
 10430344 Il2rb Interleukin 2 receptor, beta chain 1.69
 10523128 Ppbp Chemokine (C-X-C motif) ligand 7 –2.17
 10345752 Il1r2 Interleukin 1 receptor, type II −2.27
Inflammation    
 10531126 Igj Immunoglobulin joining chain 17.25
 10496555 Gbp1 Guanylate binding protein 1 7.88
 10403069 Igh-6 Immunoglobulin heavy constant mu 7.43
 10545569 Reg3g Regenerating islet-derived 3 gamma 4.61
 10502801 H28 Histocompatibility 28 3.3
 10364542 CFD Complement factor D 3.09
 10563602 Saa4 Serum amyloid A 4 2.81
 10576757 Fcer2a Fc receptor, IgE, low affinity II, alpha polypeptide 2.41
 10466172 Ms4a1 Membrane-spanning 4-domains, subfamily A, member 1 2.39
 10562169 Hamp Hepcidin antimicrobial peptide 2.38
 10551025 Cd79a CD79A antigen 2.11
 10531987 Gbp4 Guanylate binding protein 4 2.11
 10437224 Mx2 Myxovirus (influenza virus) resistance 2 2.1
 10441233 Mx1 Interferon-induced GTP-binding protein Mx1 1.96
 10500677 CD2 CD2 antigen 1.85
 10450675 H2-T24 Histocompatibility 2, T region locus 24 1.81
 10451287 Isg15 ISG15 ubiquitin-like modifier 1.81
 10531994 Mpa2l Guanylate binding protein 6 1.79
 10398121 Bdkrb1 Bradykinin receptor, beta 1 1.76
 10399710 Rsad2 Radical S-adenosyl methionine domain containing 2 1.75
 10435982 Btla B and T lymphocyte associated 1.74
 10468898 Lax1 Lymphocyte transmembrane adaptor 1 1.71
 10547894 CD4 CD4 antigen 1.7
 10444821 H2-Q8 Histocompatibility 2, Q region locus 8 1.69
 10444236 H2-DMb2 Histocompatibility 2, class II, locus Mb2 1.67
 10372652 Lyz1 Lysozyme 1 1.66
 10574098 Nlrc5 NOD-like receptor C5 1.66
 10601385 Tlr13 Toll-like receptor 13 −1.66
 10560242 C5ar1 Complement component 5a receptor 1 −1.72
 10541614 Clec4d C-type lectin domain family 4, member d −1.78
 10347335 Slc11a1 Solute carrier family 11, member 1 −1.85
 10416837 Irg1 Immunoresponsive gene 1 −2.08
 10493831 S100a8 S100 calcium binding protein A8 −2.63
 10349648 Ctse Cathepsin E −2.77
Cell adhesion molecule    
 10433172 Glycam1 Glycosylation dependent cell adhesion molecule 1 1.98
 10500677 CD2 CD2 antigen 1.85
 10450675 H2-T24 Histocompatibility 2, T region locus 24 1.81
 10547894 CD4 CD4 antigen 1.7
 10444821 H2-Q8 Histocompatibility 2, Q region locus 8 1.69
 10444236 H2-DMb2 Histocompatibility 2, class II, locus Mb2 1.67
 10562720 Siglece Sialic acid binding Ig-like lectin E −1.78
 10557862 Itgam Integrin alpha M −2.04
Transcription    
 10404389 Irf4 Interferon regulatory factor 4 (TF) 2.06
 10585276 Pou2af1 POU class 2 associating factor 1 2.09
 10562812 Spib Spi-B transcription factor (Spi-1/PU.1 related) (TF) 1.83
 10360406 Ifi205 interferon activated gene 205 1.65
 10390691 Nr1d1 Nuclear receptor subfamily 1, group D, member 1 (TF) 1.7
 10460585 Fosl1 Fos-like antigen 1 −1.85
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