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Table 3 Validation of differentially expressed genes induced by bleomycin in lung tissues from both Fra-1 +/+ and Fra-1 ∆/∆ mice

From: Expression profiling of genes regulated by Fra-1/AP-1 transcription factor during bleomycin-induced pulmonary fibrosis

Affymetrix ID Symbol Gene title Micro array qRT-PCR
    KOT vs. WTT KOT vs. WTT
    Fold change Fold change
10487588 Il1a Interleukin 1 alpha 1.87 3.40 ± 1.68*
10404389 Irf4 Interferon regulatory factor 4 (TF) 2.06 3.29 ± 1.08*
10597420 Ccr4 C-C chemokine receptor type 4 1.78 1.68 ± 0.18*
10545569 Reg3g Regenerating islet-derived 3 gamma 4.61 6.89 ± 0.86*
10493831 S100a8 S100 calcium binding protein A8 −2.63 -3.57±1.70*
  1. Data are presented as mean ± SD (n=3-4). *P<0.05, WTT vs KOT after bleomycin treatment.