Table 4 Differentially expressed genes and their GO terms related to pigmentation and melanogenesis in black versus white sheep skin
From: Skin transcriptome profiles associated with coat color in sheep
GO terms | Genes | Relative expression in black vs white sheep skin | Fold change | FDR p-value | Corrected p-value of GO term |
|---|---|---|---|---|---|
Developmental pigmentation | Tyrosinase | Up-regulation | 96.88 | 1.89 × 10-137 | 0.00273 |
G-protein coupled receptor 143 | Up-regulation | 35.63 | 1.32 × 10-28 | ||
Pallidin-like protein | Down-regulation | 0.16 | 1.47 × 10-17 | ||
P protein-like | Up-regulation | 17.65 | 4.78 × 10-5 | ||
Melanophilin | Up-regulation | 27.75 | 1.94 × 10-158 | ||
Pigment cell differentiation | Pallidin-like protein | Down-regulation | 0.16 | 1.47 × 10-17 | 1 |
P protein-like | Up-regulation | 17.65 | 4.78 × 10-5 | ||
Melanophilin | Up-regulation | 27.75 | 1.94 × 10-158 | ||
Cellular pigmentation and pigment granule localization | G-protein coupled receptor 143 | Up-regulation | 35.63 | 1.32 × 10-28 | 1 |
Melanophilin | Up-regulation | 27.75 | 1.94 × 10-158 | ||
Pigment metabolic process involved in developmental pigmentation and pigmentation | Tyrosinase | Up-regulation | 96.88 | 1.89 × 10-137 | 1 |
G-protein coupled receptor 143 | Up-regulation | 35.63 | 1.32 × 10-28 | ||
P protein-like | Up-regulation | 17.65 | 4.78 × 10-5 | ||
Melanin metabolic process | Aralkylamine N-acetyltransferase (AANAT) | Up-regulation | 9.80 | 7.9 × 10-5 | 1 |
Chain E, Crystal Structure Of The 14-3-3 Zeta:serotonin N- Acetyltransferase | Up-regulation | 7.84 | 1.44 × 10-6 | ||
Tyrosinase | Up-regulation | 96.88 | 1.89 × 10-137 | ||
P protein-like | Up-regulation | 17.65 | 4.78 × 10-5 | ||
Membrane-associated transporter protein-like isoform 1 | Up-regulation | 32.75 | 1.03 × 10-42 | ||
Membrane-associated transporter protein-like isoform 2 | Up-regulation | 4099.12 | 3.46 × 10-13 |