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Table 4 Differentially expressed genes and their GO terms related to pigmentation and melanogenesis in black versus white sheep skin

From: Skin transcriptome profiles associated with coat color in sheep

GO terms Genes Relative expression in black vs white sheep skin Fold change FDR p-value Corrected p-value of GO term
Developmental pigmentation Tyrosinase Up-regulation 96.88 1.89 × 10-137 0.00273
G-protein coupled receptor 143 Up-regulation 35.63 1.32 × 10-28
Pallidin-like protein Down-regulation 0.16 1.47 × 10-17
P protein-like Up-regulation 17.65 4.78 × 10-5
Melanophilin Up-regulation 27.75 1.94 × 10-158
Pigment cell differentiation Pallidin-like protein Down-regulation 0.16 1.47 × 10-17 1
P protein-like Up-regulation 17.65 4.78 × 10-5
Melanophilin Up-regulation 27.75 1.94 × 10-158
Cellular pigmentation and pigment granule localization G-protein coupled receptor 143 Up-regulation 35.63 1.32 × 10-28 1
Melanophilin Up-regulation 27.75 1.94 × 10-158
Pigment metabolic process involved in developmental pigmentation and pigmentation Tyrosinase Up-regulation 96.88 1.89 × 10-137 1
G-protein coupled receptor 143 Up-regulation 35.63 1.32 × 10-28
P protein-like Up-regulation 17.65 4.78 × 10-5
Melanin metabolic process Aralkylamine N-acetyltransferase (AANAT) Up-regulation 9.80 7.9 × 10-5 1
Chain E, Crystal Structure Of The 14-3-3 Zeta:serotonin N- Acetyltransferase Up-regulation 7.84 1.44 × 10-6
Tyrosinase Up-regulation 96.88 1.89 × 10-137
P protein-like Up-regulation 17.65 4.78 × 10-5
Membrane-associated transporter protein-like isoform 1 Up-regulation 32.75 1.03 × 10-42
Membrane-associated transporter protein-like isoform 2 Up-regulation 4099.12 3.46 × 10-13