Figure 4

Archaeal nucleosome profiles in vivo are reproduced in vitro. (a) Profiles of the archaeal nucleosomes assembled in vivo and in vitro by HTkA and HTkB between nucleotide positions 5,000 and 10,000 on the T. kodakarensis genome. The organization of T. kodakarensis genes in this region is shown between upper and lower panels [34, 39, 42]. (b). The occurrence of nucleosome positions relative to the start codon of all open reading frames (ORFs), assembled by HTkA in vivo (blue line) and in vitro (green line), and by HTkB in vivo (red line) and in vitro (black line) normalized to the total number of nucleosomal reads from each sequencing experiment.