Figure 4

QQ plot of associations between trait-associated SNPs and miRNA expression in liver. We considered the associations between the trait-associated SNPs from the NHGRI catalog of genome-wide association studies and miRNA expression in liver and found an excess of significant regulatory signals on miRNA expression. Shown here is the global distribution of p-values from the association with miRNA expression for the NHGRI SNPs, with deviation from expectation for the most significant associations.