The transcriptomic responses of coral to immune challenge. (Upper) The acute transcriptomic responses to MDP and Poly I:C are largely discrete. Relatively little overlap was observed between the responses to the bacterial cell-wall derivative MDP and the dsRNA mimic Poly I:C. “No hit” indicates that no significant matches were detected by BlastX searching of Genbank using E-5 as the significance cutoff. (Lower) The 15 transcriptome clusters differentially regulated under both MDP and Poly I:C challenge; up-regulated clusters are shown in green, down-regulation is indicated in red. BlastX comparisons were carried out against the NR database via NCBI using a cutoff of E-5.