Skip to main content

Table 1 Non-conservative amino acid exchanges (Dayhoff matrix index < 5) in selected proteins* of clone CHA strains

From: Intraclonal genome diversity of Pseudomonas aeruginosa clones CHA and TB

Locus_tag

Name

Encoded product

aa exchange

PA0247

PobA

p-hydroxybenzoate hydroxylase

T98M

PA0595

OstA

organic solvent tolerance protein precursor involved in outer membrane biogenesis

M907T

PA0831

OruR

transcriptional regulator of ornithine utilization

W197C

PA1148

ToxA

exotoxin A precursor

F22S

PA1712

ExsB

exoenzyme S synthesis protein B

R52G

PA1717

PscD

type III secretion export protein

V346E

PA1718

PscE

type III secretion export protein

C40G

PA2236

PslF

glycosyl transferase, Psl exopolysaccharide biosynthesis

Y247D

PA3061

PelD

membrane-bound c-di-GMP-specific receptorregulating Pel exopolysaccharide production

Y208H

PA3063

PelB

Pel exopolysaccharide biosynthesis

W791L

PA3344

RecQ

ATP dependent DNA helicase

R571C

PA3805

PilF

pilus biogenesis, outer membrane pilotin for localization and multimerization of secretin PilQ

L243P

PA3810

HscA

molecular chaperone

R285G

PA3910

EddA

extracellular DNA degradation protein

P368L

PA3946

RocS1

sensor of two-component system controlling cupC fimbrial and efflux pump gene expression

I399S

PA4085

CupB2

periplasmic chaperone

H242L

PA4086

CupB1

major pilus subunit

Q102T; V154E

PA4776

PmrA

two component regulatory system modulating resistance to cationic antimicrobial peptides

L71R

PA4777

PmrB

two component regulatory system modulating resistance to cationic antimicrobial peptides

Y345H

PA5483

AlgB

two component response regulator controlling alginate biosynthesis

L382R

PA5484

KinB

two component sensor kinase (negative regulation of alginate production, positive regulation of virulence-associated phenotypes)

Y50H

PA5493

PolA

DNA polymerase I

C882R

  1. Exchanges are given in comparison to protein sequences from the PAO1 reference.
  2. *The function of the encoded gene product has been experimentally demonstrated (annotation class I).