Laser microdissection coupled with RNA-seq analysis of porcine enterocytes infected with an obligate intracellular pathogen (Lawsonia intracellularis)

Table 3 Functional clustering associated with genes differentially expressed in Lawsonia -infected enterocytes

Gene Symbol	Gene product	ln(fold change)
Clustering
Positive regulation of transcription
TEF1	Transcriptional enhancer factor 1	2.2
SMARCC2	SWI/SNF complex subunit SMARCC2-like	2.3
SOX-9	Transcription factor SOX-9	2.6
FHL2	Four and a half LIM domains 2	2.1
Mitotic cell cycle-associated genes
CDK2	Cyclin-dependent kinase 2	2.6
RHOA	Ras homolog family member A	2.2
RHOB	Ras homolog family member B	2.2
RRAGA	Ras-related GTP-binding protein A	2.3
RPL24	60S ribosomal protein L24-like	2.7
SKA2	Spindle and kinetochore-associated protein 2-like	2.1
PSMA1	Proteasome subunit alpha type-1-like	2.4
Pro-apoptosis-related genes
SLAM7	Signaling lymphocytic activation molecule 7	−4.6
C6	Complement component C6	2.3
C9	Complement component C9	3.5
PRDX1	Peroxiredoxin 1	2.2
SST	Somatostatin	−3.4
TNFSF10	Tumor necrosis factor ligand 10	−2.5
VAV2	Vav 2 guanine nucleotide exchange factor	−2.1
Anti-apoptosis-related genes
DAD1	Defender against cell death 1	2.3
NME2	Non-metastatic cells protein	2.9
PRNP	Prion protein	2.6
PPP2CB	Protein phosphatase 2, catalytic subunit, beta isozyme	2.1
RHOA	Ras homolog family member A	2.2
TPT1	Translationally-controlled tumor protein-like	2.7
ERBB3	Receptor erythroblastic leukemia viral oncogene	2.2

ISSN: 1471-2164