Table 2 Classification of primary and secondary gastrin induced genes lower expressed in transiently treated cells
| Â | Primary genes1(N=115) | Secondary genes2(N=48) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Fraction | ||||||||||||
Per cent (%) genes in each group: | 100 | 90 | 70 | 74 | 65 | 40 | 0 | 10 | 9 | 7 | 30 | 50 |
Temporal profiles 3 | a | b | c | d | e | f | a | b | c | d | e | f |
Molecular function 4 ( N=163) | 5 | 9 | 16 | 20 | 48 | 17 | 0 | 1 | 2 | 2 | 22 | 21 |
Regulation of gene expression (N=22) | 3 | 1 | 6 | 7 | 0 | 1 | 0 | 0 | 0 | 2 | 1 | 1 |
 Transcription factors | 3 | 0 | 3 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
 Co-transcription factors | 0 | 1 | 3 | 2 | 0 | 1 | 0 | 0 | 0 | 2 | 1 | 0 |
Signal transduction (N=44) | 0 | 4 | 4 | 7 | 15 | 4 | 0 | 0 | 1 | 0 | 5 | 4 |
 Receptors | 0 | 0 | 0 | 2 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
 Ligands | 0 | 0 | 2 | 1 | 6 | 2 | 0 | 0 | 1 | 0 | 1 | 2 |
 Intracellular signalling proteins | 0 | 4 | 2 | 4 | 8 | 1 | 0 | 0 | 0 | 0 | 3 | 2 |
Transporters (N=15) | 0 | 2 | 0 | 1 | 7 | 0 | 0 | 0 | 1 | 0 | 1 | 3 |
 Channel and/or ER related | 0 | 1 | 0 | 1 | 6 | 0 | 0 | 0 | 1 | 0 | 0 | 3 |
 Other transporters | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Protein Binding (N=23) | 0 | 1 | 1 | 2 | 9 | 3 | 0 | 0 | 0 | 0 | 2 | 4 |
 Chaperone activity | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 4 |
 Other protein binding | 0 | 0 | 1 | 2 | 8 | 2 | 0 | 0 | 0 | 0 | 1 | 0 |
Enzymes (N=39) | 0 | 0 | 2 | 1 | 11 | 6 | 0 | 0 | 0 | 0 | 11 | 8 |
 Proteases | 0 | 0 | 2 | 0 | 4 | 1 | 0 | 0 | 0 | 0 | 0 | 6 |
 Aminoacyl tRNA synthases | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6 | 0 |
 Other enzymes | 0 | 0 | 0 | 1 | 7 | 5 | 0 | 0 | 0 | 0 | 5 | 2 |
Other functions (N=20) | 2 | 1 | 3 | 2 | 6 | 3 | 0 | 0 | 0 | 0 | 2 | 1 |