Skip to main content

Table 2 Annotated probe sets with a significant effect for artery and age x artery interaction

From: Gene expression differences during the heterogeneous progression of peripheral atherosclerosis in familial hypercholesterolemic swine

Probe Set ID

Gene Symbol

Gene Description

Bits1

E-value2

Effect for age FDR3

Effect for artery FDR3

Interaction effect FDR3

1 year contrast FDR3

2 year contrast FDR3

Human ortholog

Heatmap cluster

Ssc.14126.1.A1_at

FAM65B5

Homo sapiens family with sequence similarity 65, member B

238

0

0.07

0.01

0.03

0.01

0.55

FAM65B

A

Ssc.15285.1.S1_at

TPPP5

Bos taurus tubulin polymerization promoting protein

186

1.00E-44

0.69

0

0.02

0

0.09

TPPP

A

Ssc.31132.1.A1_at

TRAF3IP25

Bos taurus TRAF3 interacting protein 2

1370

0

0.91

0.04

0.03

0.01

0.98

TRAF3IP2

A

Ssc.5052.1.S1_at

FKBP155

Homo sapiens FK506 binding protein 15

2159

0

0.32

0.02

0.04

0.72

0.02

FKBP15

A

Ssc.15541.1.A1_at

PAMR15

Bos taurus regeneration associated muscle protease

1929

0

0.41

0.02

0.04

0.01

0.68

PAMR1

B

Ssc.16614.1.A1_at

PPP1R12A4

Protein phosphatase 1 regulatory subunit 12A

  

0.07

0.01

0.04

0.4

0.01

PPP1R12A

B

Ssc.21536.2.S1_at

PDE5A6

Homo sapiens phosphodiesterase 5A, cGMP-specific

282

2.00E-64

0.36

0

0.05

0.03

0

PDE5A

B

Ssc.21845.1.S1_at

OPHN14

Oligophrenin 1

  

0.91

0.04

0.04

0.98

0.02

OPHN1

B

Ssc.10497.1.S1_at

SCUBE36

signal peptide, CUB domain, EGF-like 3

526

8.00E-146

0.2

0.03

0.04

0.01

0.96

SCUBE3

C

Ssc.15046.1.A1_at

NCOA75

Bos taurus nuclear receptor coactivator 7

498

0

0.12

0.01

0.05

0.01

0.36

NCOA7

C

Ssc.17488.1.S1_at

PAN34

poly(A) specific ribonuclease subunit homolog

  

0.02

0.01

0.02

0.43

0.01

PAN3

C

Ssc.21735.1.S1_s_at

NPHP15

Bos taurus nephronophthisis 1

615

0

0.31

0.01

0.03

0.66

0.01

NPHP1

C

Ssc.8097.1.A1_at

RAB185

RAB18, member RAS oncogene family

322

2.00E-84

0.1

0.01

0.01

0

0.83

RAB18

C

Ssc.1205.1.S1_at

NR2F25

Macaca mulatta nuclear receptor subfamily 2, group F, member 2, transcript variant 2

438

0

0.34

0.03

0.05

0.01

0.9

NR2F2

D

Ssc.21644.1.S1_at

STT3A5

PREDICTED: Pan troglodytes integral membrane protein 1, transcript variant 3

98

9.00E-18

0.44

0.03

0.03

0.01

0.99

SST3A

D

Ssc.9029.1.S1_at

CST35

Homo sapiens cystatin C

153

3.00E-34

0.16

0.05

0.01

0.3

0.01

CST3

D

Ssc.17115.1.A1_at

TMEM435

Bos taurus transmembrane protein 43

1403

0

0.68

0.01

0.03

0

0.39

TMEM43

E

Ssc.19358.1.S1_at

ZDHHC95

Homo sapiens zinc finger, DHHC-type containing 9

1834

0

0.31

0.04

0.05

0.95

0.03

ZDHHC9

E

Ssc.5605.1.A1_at

ITPR14

Inositol 1,4,5-trisphosphate receptor type 1

  

0.34

0.04

0.02

0.54

0.02

ITPR1

E

Ssc.1362.1.S1_at

DBNL5

Bos taurus drebrin-like

785

0

0.29

0.02

0.03

0.91

0.01

DBNL

F

Ssc.16682.1.S1_at

RRP1B6

Homo sapiens ribosomal RNA processing 1 homolog B

394

9.00E-95

0.69

0.05

0.05

0.99

0.03

RRP1B

F

Ssc.27980.1.A1_at

FAM70A5

Homo sapiens family with sequence similarity 70, member A

579

0

0.07

0.01

0.03

0.37

0.01

FAM70A

F

Ssc.29681.1.A1_at

CCDC486

Bos taurus coiled-coil domain containing 48

68

1.00E-06

0.43

0.02

0.05

0.01

0.65

CCDC48

F

Ssc.3348.1.S1_at

CD975

Homo sapiens CD97 molecule

517

0

0.02

0

0.05

0

0.04

CD97

F

Ssc.4643.1.A1_at

NR4A25

Homo sapiens nuclear receptor subfamily 4, group A, member 2

400

0

0.03

0.02

0.05

0.01

0.77

NR4A2

F

Ssc.5113.2.A1_at

RPE5

Bos taurus ribulose-5-phosphate-3-epimerase

204

0

0.41

0

0.04

0.01

0

RPE

F

Ssc.6463.1.A1_at

MYD885

Homo sapiens myeloid differentiation primary response gene

658

0

0.2

0.03

0.04

0.95

0.02

MYD88

F

Ssc.10406.1.A1_at

THBS14

Thrombospondin 1 precursor

  

0.13

0

0.03

0

0.04

THBS1

G

Ssc.13002.1.S1_at

PPP1R14A5

Sus scrofa protein phosphatase 1, regulatory (inhibitor) subunit 14A

521

0

0.61

0.05

0.05

0.99

0.03

PPP1R14A

G

Ssc.1509.1.S1_at

TNFRSF216

Bos taurus tumor necrosis factor receptor superfamily, member 21

1199

0

0.36

0.05

0.04

0.02

0.97

TNFRSF21

G

Ssc.17903.1.A1_at

ACYP14

Acylphosphatase, organ-common type isozyme

  

0.71

0.01

0.04

0

0.17

ACYP1

G

Ssc.22406.1.A1_at

AQP15

Bos taurus aquaporin 1

1211

0

0.27

0.01

0.05

0.01

0.46

AQP1

G

Ssc.4707.1.A1_at

KITLG5

Homo sapiens KIT ligand

161

1.00E-36

0.16

0.03

0.03

0.01

0.99

KITLG

G

Ssc.5844.1.A1_at

PTCD35

Homo sapiens Pentatricopeptide repeat domain 3

1600

0

0.06

0.04

0.02

0.01

0.6

PTCD3

G

Ssc.6788.1.A1_at

SORBS26

Homo sapiens sorbin and SH3 domain containing 2

452

1.00E-123

0.34

0.02

0.04

0.01

0.59

SORBS2

G

Ssc.8683.1.S1_at

PLN5

Bos taurus phospholamban

129

5.00E-27

0.17

0

0.03

0.02

0

PLN

G

Ssc.9527.1.S1_at

NPNT5

Homo sapiens nephronectin

1017

0

0.28

0.01

0.03

0

0.28

NPNT

G

Ssc.9714.2.S1_at

LMO44

Bos taurus LIM domain only 4

747

0

0.61

0.01

0.05

0

0.19

LMO4

G

Ssc.17370.1.A1_at

ADRA1B5

Homo sapiens adrenergic, alpha-1B-, receptor

133

2.00E-28

0.14

0

0.05

0

0.01

ADRA1B

H

Ssc.20476.1.S1_at

CR1L4

Complement C4b binding protein CR-1 like

  

0.41

0.01

0.04

0

0.15

CR1L

H

Ssc.26444.1.A1_at

FARP16

Bos taurus FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1

533

5.00E-148

0.09

0.01

0.05

0.01

0.34

FARP1

H

Ssc.3034.1.S1_at

SCAMP25

Homo sapiens secretory carrier membrane protein 2

1231

0

0.55

0.02

0.02

0.93

0.01

SCAMP2

H

Ssc.4216.1.S1_at

RNPEP5

Homo sapiens arginyl aminopeptidase

1451

0

0.26

0.04

0.04

0.92

0.03

RNPEP

H

Ssc.8492.1.A1_at

RIMS24

Regulating synaptic membrane exocytosis protein 2

  

0.94

0.05

0.03

0.01

0.84

RIMS2

H

Ssc.13576.1.S1_at

IFT575

Bos taurus intraflagellar transport 57 homolog

1982

0

0.09

0.02

0.02

0.89

0.01

ITF57

I

Ssc.24231.1.S1_at

CBL5

Homo sapiens Cas-Br-M (murine) ecotropic retroviral transforming sequence

204

0

0.87

0.02

0.05

0.69

0.02

CBL

I

Ssc.29996.1.A1_at

DPP104

dipeptidylpeptidase 10 isoform1

  

0.68

0.01

0.02

0.72

0.01

DPP10

I

Ssc.23484.1.A1_a_at

SCARB25

Bos taurus scavenger receptor class B, member 2

141

7.00E-31

0.08

0.05

0.04

0.01

0.93

SCARB2

J

Ssc.24920.2.S1_a_at

DUS2L5

Bos taurus dihydrouridine synthase 2-like, SMM1 homolog

1528

0

0.12

0.02

0.04

0.57

0.01

DUS2L

J

Ssc.5587.1.A1_at

NID15

Homo sapiens nidogen 1

262

0

0.86

0

0.01

0.29

0

NID1

J

Ssc.21655.1.A1_at

GDNF5

Mus musculus glial cell line derived neurotrophic factor

202

0

0.11

0

0.03

0

0.1

GDNF

K

Ssc.9436.1.A1_at

SETBP15

Homo sapiens SET binding protein 1

232

0

0.06

0

0.02

0

0.14

SETBP1

K

Ssc.10966.1.A1_at

RBBP74

Histone acetyltransferase type B subunit 2

  

0.54

0

0.03

0.06

0

RBBP7

L

Ssc.23899.1.A1_at

MKX5

Homo sapiens mohawk homeobox

400

0

0.77

0

0.02

0

0.13

MKX

L

Ssc.8790.1.A1_at

CCL284

Small inducible cytokine A28 precursor

  

0.52

0.03

0.03

0.95

0.02

CCL28

L

Ssc.14335.1.A1_at

SH2D4B4

SH2 domain containing 4B

  

0.9

0.01

0.02

0.72

0.01

SH2D4B

M

  1. 1Bit score provides a measure of the quality of the alignment. 2Number of hits one can “expect” to see by chance when searching a database of a particular size 3False discovery rate. 4Annotation from AffymetrixNetAffx.5Annotation from ANEXdb: Animal Expression Database. 6Human ortholog from NCBI BLASTn.