Skip to main content

Table 7 Correlation of HSF1 binding following heat shock and subsequent changes in the transcription level

From: Impact of heat shock transcription factor 1 on global gene expression profiles in cells which induce either cytoprotective or pro-apoptotic response following hyperthermia

  Binding of HSF1
Induction Repression
  Number of genes % of all induced % of all bound Number of genes % of all repressed % of all bound
Spermatocytes HS_38°C 2 0.39% 0.18% 104 11.44% 9.52%
Spermatocytes HS_43°C 1 5.56% 0.06% 36 9.94% 2.02%
Hepatocytes HS_43°C 11 7.10% 1.63% 3 2.26% 0.44%
  1. For HSF1 binding values AB1-AB0 ≥ 15 and FDR < 0.05 were taken into consideration; in case of changes in expression level – range of SLRs presented in Table 1.