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Table 7 Correlation of HSF1 binding following heat shock and subsequent changes in the transcription level

From: Impact of heat shock transcription factor 1 on global gene expression profiles in cells which induce either cytoprotective or pro-apoptotic response following hyperthermia

 

Binding of HSF1

Induction

Repression

 

Number of genes

% of all induced

% of all bound

Number of genes

% of all repressed

% of all bound

Spermatocytes HS_38°C

2

0.39%

0.18%

104

11.44%

9.52%

Spermatocytes HS_43°C

1

5.56%

0.06%

36

9.94%

2.02%

Hepatocytes HS_43°C

11

7.10%

1.63%

3

2.26%

0.44%

  1. For HSF1 binding values AB1-AB0 ≥ 15 and FDR < 0.05 were taken into consideration; in case of changes in expression level – range of SLRs presented in Table 1.
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BMC Genomics

ISSN: 1471-2164

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