Figure 1

Stringent response-regulated genes of Brucella suis 1330 have been classified into 19 functional categories. A total of 379 genes were differentially regulated in minimal medium, representing 11.6% of the Brucella genome. “Up-” (red bars) and “Down-regulated” (blue bars) refers to the wild-type situation, in the presence of functional Rsh. A: Amino acid metabolism; B: Cell Division; C: Cell envelope; D: Central intermediary metabolism; E: Chemotaxis and motility; F: Cofactor and carrier biosynthesis; G: Detoxification; H: DNA/RNA metabolism; I: Energy metabolism; J: Fatty acid metabolism; K: Nitrogen metabolism; L: Protein metabolism; M: Protein modification and repair; N: Regulation; O: Stress and adaptation/chaperones/protein folding; P: Sugar metabolism; Q: Transport systems; R: Transposon function; S: Unknown function.