qPCR evaluation of the twelve immunogenes with betweenness scores greater than 10 in the control and HPS-infected samples. ARG2, BCL6, C1R, ST6GAL1, CFB, IFIT1, ASHA2, ADAM17, ADM and CD163 were up-regulated in HPS-infected samples (red bars) compared with normal controls (blue bars), and CD1D and PAK1 were down-regulated. The vertical axis denotes the fold change calculated based on the mean intensity value from each individual within each group using the comparative Ct method. The expression differences were analyzed with T-tests. Asterisks (*) above the bars represent that the expression differences of the genes between the control and infected groups are significant at the level of p ≤ 0.05.