Table 3 Top candidate genes that are differentially expressed between RH-ERP and GT1
From: Genetic basis for phenotypic differences between different Toxoplasma gondii type I strains
A. Candidate genes containing 5′ and 3′ UTR SNP/indels and are differentially expressed between RH-ERP and GT1 | ||||
Position | ToxoDB GT1 ID | ToxoDB annotation | Fold change RH-ERP/ GT1 (Microarray) | Possible involvement in Toxoplasma process |
5′ UTR | TGGT1_041490 | dihydrolipoamid dehydrogenase, putative | 1.7 | Growth |
5′ UTR | TGGT1_027570 | microneme protein, putative | 1.6 | Invasion |
3′ UTR | TGGT1_114880 | tRNA splicing 2′ phosphotransferase, putative | 1.6 | Translation |
5′ UTR | TGGT1_090150 | NBP2B protein, putative | 1.6 | Unknown |
5′ UTR | TGGT1_073790 | transporter, major facilitator family protein | -5.1 | Growth |
B. Candidate genes consistently differentially expressed between RH-ERP and GT1 | Â | |||
ToxoDB GT1 ID | ToxoDB annotation | Fold change RH-ERP/GT1 (Microarray) | Possible involvement in Toxoplasma process | |
TGGT1_098460 | ankyrin repeat-containing protein | 12.1 | Transcriptional control | |
TGGT1_073210 | hypothetical protein | 5.7 | Unknown | |
TGGT1_020630 | hypothetical protein (contains glycosyltransferase 17 family) | 5.7 | Unknown | |
TGGT1_051960 | ABC transporter transmembrane region domain-containing protein | 3.0 | Growth | |
TGGT1_030200 | Peptidyl-tRNA hydrolase PTH2 domain-containing protein | 2.3 | Growth | |
TGGT1_000480 | GRA12 homologue | 2.0 | Growth | |
TGGT1_126470 | hypothetical protein | -2.1 | Unknown | |
TGGT1_048210 | rhoptry kinase family protein ROP38 (ROP38) | -3.7 | Host cell modulation | |
TGGT1_047990 | rhoptry kinase family protein ROP29 (ROP29) | -4.0 | Host cell modulation | |
TGGT1_081480 | zinc finger (CCCH type) motif-containing protein | -8.0 | Transcriptional control | |
TGGT1_021770 | microneme protein, putative | -9.2 | Invasion | |
TGGT1_126670 | rhoptry protein ROP8 (ROP8) | -11.3 | Host cell modulation | |