Skip to main content
Figure 4 | BMC Genomics

Figure 4

From: Coexpression analysis of large cancer datasets provides insight into the cellular phenotypes of the tumour microenvironment

Figure 4

Network derived from testicular cancer dataset (Pearson correlation threshold r = 0.75). a) Network with only edges showing allowing visualization of the inherent complex topology of the graph and b) with nodes shown where nodes are coloured according to cluster membership. c) Graph with selected clusters shown and d) the average expression profile of genes within those clusters. (Cluster colour code is maintained across graphs in this figure). Cluster 68 is highly enriched with endothelial marker genes and cluster 23 contains many transcripts known to be associated with extracellular matrix. The last three selected clusters can be associated with different aspects of the immune infiltrate in these tumours. Cluster 2 contains many know markers of T-cell and B-cells, cluster 4 (also shown in Figure 2) is enriched with many known macrophage expressed genes and cluster 10 is highly enriched with many interferon response genes.

Back to article page