Figure 1

The comparison of Site-specific methylation levels at IGF2 DMR among normal pregnancy, gestational hypertension and preeclampsia. There were significant differences in methylation levels (Y-axle) of site 3, 6 and 7 (*: P<0.05 for all) but not the site 4, 9 and 10 among three groups (P>0.05 for all). The methylation levels of site 3, 6 and 7 were significantly lower in preeclampsia than normal pregnancy (P=0.045, 0.009, 0.048, respectively), but not significantly different between normal pregnancy and gestational hypertension, or between gestational hypertension and preeclamspsia (P>0.05 for all).