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Table 1 Cytotoxicity of L-OHP in parental and their L-OHP resistant variants (Colo320/Colo320R and HT-29/HT-29R)

From: Oxaliplatin induces different cellular and molecular chemoresistance patterns in colorectal cancer cell lines of identical origins

Cell lines Colo320 Colo320R HT-29 HT-29R
IC50 (μg/ml) 7.546 ± 0.5970 20.85 ± 1.069 22.31 ± 2.717 56.80 ± 5.065
  1. Values are means ± SEM in triplicate, in 3 separate experiments, after 24 h exposure of the cells to varying concentrations of L-OHP (0.001-300 μg/ml).