|
Interferon signaling
|
2,51E-05
|
1.94E-01
|
IFIT3, IFIT1, IFITM1, MX1, IRF9, PSMB8, STAT1
|
|
Methylglyoxal degradation III
|
2,04E-04
|
1.74E-01
|
AKR7A3, AKR1C1/AKR1C2, AKR1B10, AKR1B1
|
|
Cholesterol biosynthesis I
|
4,17E-04
|
1E-01
|
SQLE, DHCR7, MSMO1, CYP51A1
|
|
Cholesterol biosynthesis II (via 24,25-dihydrolanosterol)
|
4,17E-04
|
1E-01
|
SQLE, DHCR7, MSMO1, CYP51A1
|
|
Cholesterol biosynthesis III (via Desmosterol)
|
4,17E-04
|
1E-01
|
SQLE, DHCR7, MSMO1, CYP51A1
|
|
LXR/RXR activation
|
7,76E-04
|
8.09E-02
|
SCD, TTR, LDLR, SREBF1, AMBP, SERPINA1, PTGS2, TLR3, IL1RAP, CYP51A1, AGT
|
|
Mevalonate pathway I
|
4,47E-03
|
1.07E-01
|
IDI1, HMGCS2, HMGCS1
|
|
Creatine-phosphate biosynthesis
|
4,90E-03
|
3.33E-01
|
CKB, CKMT1A/CKMT1B, LCMT2
|
|
Activation of IRF by Cytosolic pattern recognition receptors
|
5,75E-03
|
8.33E-02
|
DHX58, IFIH1, IRF9, STAT1, IFIT2, ISG15
|
|
Tryptophan degradation X (Mammalian, via Tryptamine)
|
1,05E-02
|
1.03E-01
|
ALDH1A3, DDC, MAOA
|
|
Zymosterol biosynthesis
|
1,17E-02
|
9.09E-02
|
MSMO1, CYP51A1
|
|
Maturity onset diabetes of young (MODY) signaling
|
1,95E-02
|
9.68E-02
|
FOXA2, FABP1, HNF4A
|
|
Eicosanoid signaling
|
2,19E-02
|
6.25E-02
|
DPEP1, PNPLA3, RARRES3, PTGS2, ALOX5
|
|
Ketogenesis
|
2,69E-02
|
9.52E-02
|
HMGCS2, HMGCS1
|
|
Acyl-CoA hydrolysis
|
3,31E-02
|
1.25E-01
|
ACOT4, HNF4A
|
|
PXR/RXR activation
|
3,47E-02
|
5.75E-02
|
SCD, NR0B2, CYP2B6, HMGCS2, HNF4A
|
|
Colorectal cancer metastasis signaling
|
3,89E-02
|
4.67E-02
|
VEGFA, MMP7, RND3, TGFB1, FZD3, GNB5, TGFB2, PTGS2, TLR3, STAT1, FNBP1, WNT5A
|
|
Aryl hydrocarbon receptor signaling
|
4,17E-02
|
4.97E-02
|
TGM2, TFF1, NR0B2, ALDH1A3, TGFB1, TGFB2, ALDH18A1,NRIP1
|
|
p38 MAPK signaling
|
4,27E-02
|
5.98E-02
|
DDIT3, TGFB1, TGFB2, MKNK2, RPS6KA2, STAT1, IL1RAP
|
|
Choline biosynthesis III
|
4.64E-02
|
9.09E-02
|
CHPT1,PLD1
|
|
Histamine degradation
|
4.64E-02
|
6.9E-02
|
ALDH1A3,ABP1
|
|
Adenosine nucleotides degradation II
|
4.64E-02
|
8E-02
|
NT5E, ADA
|
|
Wnt/β-catenin signaling
|
5E-02
|
5.2E-02
|
MMP7, CDH3, TGFB1, PPP2R3A, TGFBR3, FZD3, CD44, TGFB2, WNT5A
|
