The functional association network and the subcellular localization of its members. (A) The predicted functional association network in P. infestans. Nodes, representing proteins, are colored according to their subcellular localization approximated by Gene Ontology term. (B) Correlation of subcellular localization with predicted protein associations. The log2-fold enrichment/depletion of protein pairs where both partners are predicted to reside in the same/different subcellular localization compared to the expected numbers is displayed by the heat map (lower half of the symmetrical matrix) (values saturate at ± 1.5); the corresponding raw numbers are shown in upper half. Significant enrichment/depletion (after multiple testing correction) is indicated by “*”. The total number of proteins predicted to reside in a particular subcellular localization is displayed in brackets above the plot.