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Table 4 Comparison of SGH to Whole Genome Sequencing

From: Design and validation of a supragenome array for determination of the genomic content of Haemophilus influenzae isolates

Strain

No of clusters based on supragenome analysis

Clusters represented on chip

Number in agreement between WGS and CGH

False negatives (CGH -, WGS +) [%]

False positives (CGH +, WGS -)[%]

PittAA

2003

1849

1803

46 [2.49%]

46 [2.49%]

NML20

1838

1688

1665

23 [1.36%]

11 [0.65%]

22.1-21

1967

1811

1786

25 [1.38%]

14 [0.77%]

HI7P49HI

1897

1744

1724

20 [1.15%]

16 [0.92%]

R2846

1856

1708

1686

22 [1.29%]

20 [1.17%]

R2866

2017

1860

1837

23 [1.24%]

13 [0.70%]

R1838

1900

1748

1728

20 [1.14%]

15 [0.86%]

CZ4126-02

 

1702*

1656

46 [2.7%]

39 [2.29%]

  1. * based on WGS of CZ4126-02, and not included in SGHChip design.