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Figure 5 | BMC Genomics

Figure 5

From: Transcriptome analyses of the human retina identify unprecedented transcript diversity and 3.5 Mb of novel transcribed sequence via significant alternative splicing and novel genes

Figure 5

The effects of novel transcript features/splicing on reading frame. A) Of the 19,637 novel internal exons, 18% maintain an open reading frame (ORF), 30% result in a frameshift or contain a stop codon, and 52% are found within an untranslated region of the transcript. Of the 52% of novel exons that lie in an annotated UTR, 34% maintain an ORF (green bar) and 66% (gray bar) result in a frameshift or contain a stop codon. B) Of the 28,271 novel exon skipping events, 15% maintain an ORF, 53% result in a frameshift, and 32% are located in non-coding RNA (ncRNA). C) Of the 21,757 novel alternate 3′/5′ splice sites, 23% maintain an ORF, 56% result in a frameshift or contain a stop codon, and 21% are located in ncRNA.

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