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Table 1 Gene category overlap with modules

From: Gene bionetworks that regulate ovarian primordial follicle assembly

Module

Gene category

Gene

Over

number

representation fisher

module

fisher P-value†

overlap*

Turquoise

Ribosome

10

7.52E-08

Turquoise

cytosolic ribosome

7

2.40E-06

Turquoise

Neural tube closure

4

0.00041

Turquoise

Negative regulation of binding

5

0.00045

Turquoise

Primary neural tube formation

4

0.00056

Turquoise

Protein biosynthesis

15

0.00071

Turquoise

Glutathione metabolism

5

0.0011

Blue

Response to oxidative stress

12

1.30E-06

Blue

Regulation of anatomical structure morphogenesis

13

2.20E-06

Blue

Mesoderm development

18

1.90E-05

Blue

Angiogenesis

6

2.20E-05

Blue

Response to carbohydrate stimulus

6

3.60E-05

Blue

Regulation of axonogenesis

6

5.00E-05

Blue

Membrane raft

9

7.80E-05

Blue

negative chemotaxis

3

1.00E-04

Blue

Axon guidance

6

3.70E-03

Blue

Glutathione metabolism

3

3.10E-02

Blue

Focal adhesion

6

3.20E-02

Blue

Fc gamma R-mediated phagocytosis

4

3.60E-02

Blue

MAPK signaling pathway

6

8.50E-02

Brown

Germ cell nucleus

3

7.00E-04

Brown

Male meiosis

3

0.0015

Brown

Neurite regeneration

3

0.0031

Brown

Condensed nuclear chromosome

3

0.0041

Brown

Other oncogenesis

3

0.0074

Brown

Cell cycle

4

0.026

Brown

Olfactory transduction

12

0.065

Yellow

Hematopoietic cell lineage

3

0.0027

Yellow

Positive regulation of apoptosis

5

0.009

Yellow

Coenzyme and prosthetic group metabolism

3

0.015

yellow

Mitochondrial lumen

3

0.018

Green

proteinaceous extracellular matrix

3

0.0072

Black

Extracellular matrix

4

0.00015

Black

extracellular region

7

0.00042

Black

Response to stress

8

0.002

Black

Cell communication

6

0.0029

Black

Negative regulation of apoptosis

4

0.0029

Pink

Apical plasma membrane

3

0.0011

Pink

Protein glycosylation

3

0.0018

Magenta

Calcium mediated signaling

2

0.0066

  1. *Gene Number Module Overlap is the number of genes from that module that are in common with those in the listed physiological process or pathway (see Methods).
  2. †Fisher’s Exact test was used to calculate a p-value reflecting the probability that the specified module and pathway/process would have listed number of overlapped genes.