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Table 2 Gene connectivity ranking information

From: Gene bionetworks that regulate ovarian primordial follicle assembly

Name /

Gene description

Local

symbol gene

connectivity *

TNFRSF1A

Tumor necrosis factor receptor superfamily, member 1A

37

TGFB2

Transforming growth factor, beta 2

36

MDM2

Mdm2 p53 binding protein homolog (mouse)

27

GATA4

GATA binding protein 4

27

PPARGC1A

Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha

26

PRKCB

Protein kinase C, beta

25

TFRC

Transferrin receptor (p90, CD71)

23

ANXA5

Annexin A5

20

ANXA2

Annexin A2

20

SDC4

Syndecan 4

16

LRP2

Low density lipoprotein-related protein 2

16

GRLF1

Glucocorticoid receptor DNA binding factor 1

15

GSTP1

Glutathione S-transferase pi 1

14

HSD11B1

Hydroxysteroid (11-beta) dehydrogenase 1

13

UCP2

Uncoupling protein 2 (mitochondrial, proton carrier)

12

THRA

Thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)

10

ANPEP

Alanyl (membrane) aminopeptidase

10

IL1R1

Interleukin 1 receptor, type I

9

EPHA2

EPH receptor A2

9

CTSK

Cathepsin K

8

SMPD1

Sphingomyelin phosphodiesterase 1, acid lysosomal

8

  1. *Local connectivity is the number of regulatory connections which that gene has with other genes, identified in published literature, within the gene network of 326 genes derived from the complete set of 1081 differentially expressed genes (see Additional file 4: Figure S2).